⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27750846 | 0.76 | — | — | |
| SCHEMBL9370321 | 0.75 | — | — | |
| SCHEMBL324805 | 0.75 | — | — | |
| SCHEMBL27699481 | 0.71 | — | — | |
| SCHEMBL530947 | 0.71 | ALOX5 (0.33) | — | |
| SCHEMBL5670308 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL6277013 | 0.69 | CTSA (0.38) | — | |
| SCHEMBL9990775 | 0.68 | — | — | |
| SCHEMBL4938364 | 0.68 | ALDH1A1 (0.52) | — | |
| Hydrochloric Acid SCHEMBL9634544 | 0.67 | CTSA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270447-A1 | 2-Aryl-and 2-Heteroarylthiazolyl Compounds, Methods for Their Preparation and Use Thereof | WYETH (US) | 2009-10-29 | — | — | US | disclosed |
| WO-2009120849-A1 | 2-ARYL- AND 2-HETEROARYLTHIAZOLYL COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF | WYETH (US) | 2009-10-01 | — | — | WO | disclosed |