Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.34 |
| ▸ | ULK1 | O75385 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.34 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.34 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127415 | 0.74 | MAPT (0.36) | NPY5R | |
| SCHEMBL28393579 | 0.74 | MAPT (0.36) | NPY5R | |
| SCHEMBL129499 | 0.74 | NPY5R (0.31) | NPY5R | |
| SCHEMBL3644139 | 0.74 | NPY5R (0.31) | NPY5R | |
| SCHEMBL3858640 | 0.74 | CYP2A6 (0.47) | PIM1GSK3BNPY5R | |
| SCHEMBL128068 | 0.74 | CDK5 (0.32) | CDK5CDK5R1NPY5R | |
| SCHEMBL1408151 | 0.74 | LOXL2 (0.37) | — | |
| SCHEMBL16416921 | 0.71 | GSK3B (0.33) | CDK5CDK5R1ULK1CDK7PRKCE | |
| SCHEMBL985896 | 0.71 | GSK3B (0.46) | GSK3BSCN9A | |
| SCHEMBL7853081 | 0.71 | CCR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115919864-B | Application of azolopyrimidinamine compounds in preparing medicines for treating IBD | 中南大学湘雅三医院 | 2024-09-03 | — | — | CN | claimed |
| CN-115919864-A | Application of azolopyrimidine amine compound in preparation of medicine for treating IBD (infectious bronchitis) | 中南大学湘雅三医院 | 2023-04-07 | — | — | CN | claimed |
| US-20160295869-A1 | Combinations Comprising a Fungicidal Strain and an Active Compound | BAYER CROPSCIENCE LP | 2016-10-13 | — | — | US | claimed |
| EP-1909579-B1 | FUNGICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES | BASF SE (DE) | 2015-10-07 | — | — | EP | claimed |
| EP-2560492-B1 | FUNGICIDAL MIXTURES COMPRISING AMETOCTRADIN AND A TETRAZOLOXIME DERIVATIVE | BASF SE (DE) | 2015-03-04 | — | — | EP | claimed |
| EP-2066177-B1 | FUNGICIDAL MIXTURES OF 1-METHYLPYRAZOLE-4-YLCARBOXYLIC ACID ANILIDES AND AZOLOPYRIMIDINYLAMINES | BASF SE (DE) | 2014-12-24 | — | — | EP | claimed |
| US-20140155263-A1 | Fungicidal Mixtures Based on Azolopyrimidinylamines | BASF SE (DE) | 2014-06-05 | — | — | US | claimed |
| US-8461077-B2 | Combinations of active substances | BASF SE (DE) | 2013-06-11 | — | — | US | claimed |
| US-20130040969-A1 | Fungicidal Mixtures Based on Azolopyrimmidinylamines | BASF SE (DE) | 2013-02-14 | — | — | US | claimed |
| US-20130023412-A1 | Fungicidal Mixtures Based on Azolopyrimidinylamines | BASF SE (DE) | 2013-01-24 | — | — | US | claimed |
| US-20080234295-A1 | Fungicidal Mixtures Based on Azolopyrimidinylamines | BASF AKTIENGELSELLSCHAFT (DE) | 2008-09-25 | — | — | US | claimed |
| WO-2008092759-A2 | PESTICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES DERIVATIVES AND INSECTICIDES | BASF SE (DE) | 2008-08-07 | — | — | WO | claimed |
| WO-2008087182-A2 | FUNGICIDAL MIXTURES OF 1-METHYLPYRAZOLE-4-YLCARBOXYLIC ACID ANILIDES AND AZOLOPYRIMIDINYLAMINES | BASF SE (DE) | 2008-07-24 | — | — | WO | claimed |
| EP-1909579-A1 | FUNGICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES | BASF SE (DE) | 2008-04-16 | — | — | EP | claimed |
| CN-1972940-A | Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with a cyclic amino group as CRF receptor antagonists | TAISHO PHARMACEUTICAL CO LTD (JP) | 2007-05-30 | — | — | CN | claimed |
| WO-2007012598-A1 | FUNGICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES | BASF AKTIENGESELLSCHAFT (DE) | 2007-02-01 | — | — | WO | claimed |
| US-RE32676-E | 7-aminozolo[1,5-a]pyrimidines and fungicides containing these | BASF AKTIENGESELLSCHAFT (DE) | 1988-05-24 | — | — | US | claimed |
| EP-0141317-B1 | 7-Amino-azolo[1,5-a]pyrimidines and fungicides containing them | BASF Aktiengesellschaft (DE) | 1988-01-20 | — | — | EP | claimed |
| US-4617303-A | 7-aminoazolo[1,5-a]pyrimidines and fungicides containing these | BASF AKTIENGESELLSCHAFT (DE) | 1986-10-14 | — | — | US | claimed |
| EP-0141317-A2 | 7-Amino-azolo[1,5-a]pyrimidines and fungicides containing them | BASF Aktiengesellschaft (DE) | 1985-05-15 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023412-A1 | Fungicidal Mixtures Based on Azolopyrimidinylamines | DDT, AS3MT, AADAC | MASP2 358/4885LTA4H 1810/4885AOC3 185/4885 |
| US-20140155263-A1 | Fungicidal Mixtures Based on Azolopyrimidinylamines | DDT, STS, ARSA | MASP2 2370/4885LTA4H 4110/4885AOC3 2096/4885 |
| US-20160295869-A1 | Combinations Comprising a Fungicidal Strain and an Active Compound | O60361, SPOUT1, FBL | MASP2 3364/4885LTA4H 4363/4885AOC3 2160/4885 |
| US-20130040969-A1 | Fungicidal Mixtures Based on Azolopyrimmidinylamines | ERG28, INMT, AS3MT | MASP2 285/4885LTA4H 2282/4885AOC3 274/4885 |
| US-20080234295-A1 | Fungicidal Mixtures Based on Azolopyrimidinylamines | DDT, STS, ARSA | MASP2 2370/4885LTA4H 4110/4885AOC3 2096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.