SCHEMBL4239928

SCHEMBL4239928

CC(C)c1cc(-c2cccc(O)c2)c(O)cc1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 4/20 0.51
HSD17B1 P14061 9/20 0.45
HSD17B2 P37059 9/20 0.45
CYP3A4 P08684 3/20 0.45
CYP2C9 P11712 2/20 0.45
PELI1 Q96FA3 1/20 0.44
HSP90AB1 P08238 3/20 0.42
CYP1A2 P05177 2/20 0.42
MEN1 O00255 1/20 0.42
USP2 O75604 1/20 0.42
ALDH1A1 P00352 1/20 0.42
APP P05067 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPT P10636 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
MAPK1 P28482 1/20 0.42
CYP2C19 P33261 1/20 0.42
SNCA P37840 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21363250 0.83 HSP90AA1 (0.64) HSP90AA1HSP90AB1ALDH1A1HSD17B10ESR2
SCHEMBL4063286 0.83 HSP90AA1 (0.49) HSP90AA1CYP3A4HSP90AB1CYP1A2ALDH1A1
SCHEMBL10094321 0.80 HSD17B1 (0.47) HSP90AA1HSD17B1HSD17B2CYP3A4CYP2C9
SCHEMBL4241557 0.78 APP (0.50) HSP90AA1HSP90AB1APPMAPTSNCA
SCHEMBL28704117 0.78 HSP90AA1 (0.48) HSP90AA1HSP90AB1
SCHEMBL4383317 0.76 HSP90AA1 (0.52) HSP90AA1CYP3A4CYP2C9HSP90AB1CYP1A2
SCHEMBL15323374 0.76 HSP90AA1 (0.50) HSP90AA1HSP90AB1HSD17B10HPGDTSHR
SCHEMBL4191555 0.75 HSD17B1 (0.45) HSD17B1HSD17B2CYP3A4CYP2C9PELI1
SCHEMBL13848426 0.75 HSP90AA1 (0.60) HSP90AA1HSD17B1HSD17B2CYP3A4CYP2C9
SCHEMBL25906339 0.74 HSP90AA1 (0.60) HSP90AA1HSP90AB1ALDH1A1LMNASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009066060-A2 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE TOPOTARGET A/S (DK) 2009-05-28 WO disclosed
WO-2009066060-A2 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE TOPOTARGET A/S (DK) 2009-05-28 WO disclosed