Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 10/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30628137 | 1.00 | TSPO (1.00) | TSPOOPRK1ALB | |
| SCHEMBL15256823 | 0.93 | TSPO (0.87) | TSPOOPRK1ALB | |
| SCHEMBL7567968 | 0.88 | TSPO (0.78) | TSPOOPRK1ALB | |
| SCHEMBL13697671 | 0.85 | TSPO (0.74) | TSPOOPRK1ALB | |
| SCHEMBL22082611 | 0.82 | TSPO (0.70) | TSPOOPRK1ALB | |
| SCHEMBL18116235 | 0.81 | TSPO (0.68) | TSPO | |
| SCHEMBL14542063 | 0.80 | TSPO (0.69) | TSPOOPRK1 | |
| SCHEMBL14542053 | 0.78 | TSPO (0.64) | TSPOOPRK1ALB | |
| SCHEMBL14542066 | 0.77 | TSPO (0.62) | TSPOOPRK1ALB | |
| SCHEMBL7573859 | 0.76 | TSPO (0.69) | TSPOOPRK1ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117099-A1 | DIPEPTIDE LIGANDS OF TSPO THAT POSSESS NEUROPSYCHOTROPIC ACTIVITY | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт фармакологии имени В.В. Закусова" | 2020-06-11 | — | — | WO | disclosed |
| US-8841320-B2 | Targeted, NIR imaging agents for therapy efficacy monitoring, deep tissue disease demarcation and deep tissue imaging | VANDERBILT UNIVERSITY | 2014-09-23 | — | — | US | disclosed |
| US-8841320-B2 | Targeted, NIR imaging agents for therapy efficacy monitoring, deep tissue disease demarcation and deep tissue imaging | VANDERBILT UNIVERSITY | 2014-09-23 | — | — | US | disclosed |
| US-20130177502-A1 | Targeted, NIR Imaging Agents for Therapy Efficacy Monitoring, Deep Tissue Disease Demarcation and Deep Tissue Imaging | VANDERBILT UNIVERSITY (US) | 2013-07-11 | — | — | US | disclosed |
| US-20130177502-A1 | Targeted, NIR Imaging Agents for Therapy Efficacy Monitoring, Deep Tissue Disease Demarcation and Deep Tissue Imaging | VANDERBILT UNIVERSITY (US) | 2013-07-11 | — | — | US | disclosed |
| US-8372868-B2 | Targeted, NIR imaging agents for therapy efficacy monitoring, deep tissue disease demarcation and deep tissue imaging | VANDERBILT UNIVERSITY (US) | 2013-02-12 | — | — | US | disclosed |
| US-8372868-B2 | Targeted, NIR imaging agents for therapy efficacy monitoring, deep tissue disease demarcation and deep tissue imaging | VANDERBILT UNIVERSITY (US) | 2013-02-12 | — | — | US | disclosed |
| US-8188116-B2 | Ligand/drug conjugates; near infrared radiation imaging; peripheral benzodiazepine receptor imaging; drug delivery; drug targets; cancer, metastasis | VANDERBILT UNIVERSITY (US) | 2012-05-29 | — | — | US | disclosed |
| US-8188116-B2 | Ligand/drug conjugates; near infrared radiation imaging; peripheral benzodiazepine receptor imaging; drug delivery; drug targets; cancer, metastasis | VANDERBILT UNIVERSITY (US) | 2012-05-29 | — | — | US | disclosed |
| US-20100278739-A1 | TARGETED, NIR IMAGING AGENTS FOR THERAPY EFFICACY MONITORING, DEEP TISSUE DISEASE DEMARCATION AND DEEP TISSUE IMAGING | VANDERBILT UNIVERSITY | 2010-11-04 | — | — | US | disclosed |
| US-7754884-B2 | Targeted, NIR imaging agents for therapy efficacy monitoring, deep tissue disease demarcation and deep tissue imaging | VANDERBILT UNIVERSITY (US) | 2010-07-13 | — | — | US | disclosed |
| US-20090234162-A1 | Radioactive Halogen-Labeled Phenyloxyaniline Derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-09-17 | — | — | US | disclosed |
| US-20090142264-A1 | 18F-Labeled Phenoxyphenyl Nu-benzyl Alkanamid Derivatives for Positron Emission Tomography (PET) Imaging of Peripheral Benzodiazepine Receptor | LANGSTROM BENGT | 2009-06-04 | — | — | US | disclosed |
| US-20080293969-A1 | 18F-Labeled Daa Analogues and Method of Labeling These Analogues as Positron Emission Tomography (Pet) Tracers For Imaging Peripheral Benzodiazepine Receptors | GE HEALTHCARE LIMITED (GB) | 2008-11-27 | — | — | US | disclosed |
| US-20080031823-A1 | AGENTS FOR THERAPY EFFICACY MONITORING AND DEEP TISSUE IMAGING | US GOVERNMENT - SECRETARY FOR THE ARMY | 2008-02-07 | — | — | US | disclosed |
| US-20080031823-A1 | AGENTS FOR THERAPY EFFICACY MONITORING AND DEEP TISSUE IMAGING | US GOVERNMENT - SECRETARY FOR THE ARMY | 2008-02-07 | — | — | US | disclosed |
| WO-2007074383-A1 | 18F-LABELED PHENOXYPHENYL N-BENZYL ALKANAMID DERIVATIVES FOR POSITRON EMISSION TOMOGRAPHY (PET) IMAGING OF PERIPHERAL BENZODIAZEPINE RECEPTOR | GE HEALTHCARE LIMITED (GB) | 2007-07-05 | — | — | WO | disclosed |
| EP-1250597-A2 | IDENTIFICATION OF PERIPHERAL BENZODIAZEPINE RECEPTOR BINDING AGENTS | MITOKOR (US) | 2002-10-23 | — | — | EP | disclosed |
| US-20020039746-A1 | Methods for identifying peripheral benzodiazepine receptor binding agents | MITOKOR | 2002-04-04 | — | — | US | disclosed |
| WO-2001051922-A2 | IDENTIFICATION OF PERIPHERAL BENZODIAZEPINE RECEPTOR BINDING AGENTS | MITOKOR (US) | 2001-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080031823-A1 | AGENTS FOR THERAPY EFFICACY MONITORING AND DEEP TISSUE IMAGING | TSPO, MKI67, CNR1 | TSPO 1/4885OPRK1 34/4885ALB 2663/4885 |
| US-20080293969-A1 | 18F-Labeled Daa Analogues and Method of Labeling These Analogues as Positron Emission Tomography (Pet) Tracers For Imaging Peripheral Benzodiazepine Receptors | GABRA3, GABRE, GABRB3 | TSPO 4/4885OPRK1 33/4885ALB 3506/4885 |
| US-20100278739-A1 | TARGETED, NIR IMAGING AGENTS FOR THERAPY EFFICACY MONITORING, DEEP TISSUE DISEASE DEMARCATION AND DEEP TISSUE IMAGING | TSPO, MKI67, GABRA4 | TSPO 1/4885OPRK1 48/4885ALB 1948/4885 |
| US-20090142264-A1 | 18F-Labeled Phenoxyphenyl Nu-benzyl Alkanamid Derivatives for Positron Emission Tomography (PET) Imaging of Peripheral Benzodiazepine Receptor | ALK, GABRA4, GABRB3 | TSPO 44/4885OPRK1 54/4885ALB 2722/4885 |
| US-20130177502-A1 | Targeted, NIR Imaging Agents for Therapy Efficacy Monitoring, Deep Tissue Disease Demarcation and Deep Tissue Imaging | TSPO, MKI67, GABRA4 | TSPO 1/4885OPRK1 48/4885ALB 1948/4885 |
| US-20090234162-A1 | Radioactive Halogen-Labeled Phenyloxyaniline Derivatives | TSPO, PBRM1, PSEN1 | TSPO 1/4885OPRK1 278/4885ALB 3921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.