Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 5/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908790 | 0.84 | MIF (0.50) | MIFHSD17B1HSD17B2NOTUML3MBTL1 | |
| SCHEMBL23086229 | 0.76 | HSD17B1 (0.74) | MIFHSD17B1HSD17B2CA12CA1 | |
| SCHEMBL1119554 | 0.76 | PTGS2 (0.66) | MIFHSD17B1HSD17B2NOTUML3MBTL1 | |
| SCHEMBL23430997 | 0.76 | MAPT (0.77) | MIFHSD17B1HSD17B2CA12CA1 | |
| Bromide SCHEMBL6256547 | 0.74 | PTGS2 (0.64) | MIFHSD17B1HSD17B2NOTUML3MBTL1 | |
| SCHEMBL23028378 | 0.74 | NOTUM (0.58) | MIFHSD17B1HSD17B2NOTUML3MBTL1 | |
| SCHEMBL12599087 | 0.72 | HSD17B1 (0.74) | MIFHSD17B1HSD17B2CA12CA1 | |
| SCHEMBL4244235 | 0.72 | CYP19A1 (0.64) | MIFHDAC8PTGS2EGLN1 | |
| SCHEMBL4550718 | 0.70 | HSP90AA1 (0.51) | MIFHSD17B1HSD17B2NOTUML3MBTL1 | |
| SCHEMBL6953018 | 0.70 | FLT3 (0.77) | MIFNOTUML3MBTL1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |