Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4240357 | 0.77 | BACE1 (0.37) | BCL2L1ALOX5MEN1KMT2AHPGD | |
| SCHEMBL27920613 | 0.70 | PDE4B (0.39) | HPGDHSD17B10 | |
| SCHEMBL278522 | 0.69 | BCL2 (0.59) | ELANECTSGBCL2BCL2L1PAX8 | |
| SCHEMBL29450504 | 0.69 | BCL2 (0.59) | ELANECTSGBCL2BCL2L1PAX8 | |
| SCHEMBL4542846 | 0.69 | PAX8 (0.46) | ELANECTSGBCL2BCL2L1PAX8 | |
| SCHEMBL27967409 | 0.69 | PTPN22 (0.43) | ALOX5MEN1KMT2AHIF1AHSD17B10 | |
| SCHEMBL1644555 | 0.67 | BCL2 (0.55) | ELANECTSGBCL2BCL2L1PAX8 | |
| SCHEMBL27901201 | 0.65 | BCL2 (0.53) | ELANECTSGBCL2BCL2L1PAX8 | |
| SCHEMBL10011371 | 0.65 | BCL2 (0.53) | ELANECTSGBCL2BCL2L1PAX8 | |
| Hydrochloric Acid SCHEMBL21412101 | 0.65 | MAOA (0.37) | MEN1KMT2ACYP3A4HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |