SCHEMBL4240426

SCHEMBL4240426

N#CCc1ccc(C(C#N)(C#N)C#N)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
KMT2A Q03164 4/20 0.37
KDM4E B2RXH2 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ENPP2 Q13822 1/20 0.33
TNF P01375 1/20 0.33
PKM P14618 2/20 0.33
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
MMP3 P08254 1/20 0.32
MEN1 O00255 2/20 0.31
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GAA P10253 1/20 0.30
CYP1A1 P04798 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2154504 0.80 KMT2A (0.47) KMT2AKDM4ETDP1L3MBTL1ENPP2
SCHEMBL105433 0.77 KIF11 (0.47) ESR1ESR2KMT2AKDM4ETDP1
SCHEMBL8763137 0.77 ESR1 (0.41) ESR1ESR2KMT2AKDM4ETDP1
SCHEMBL246959 0.77 TAAR1 (0.48) KMT2AKDM4EALDH1A1
SCHEMBL10730816 0.76 ESR1 (0.39) ESR1ESR2KMT2AKDM4ETDP1
SCHEMBL7873873 0.74 PDE2A (0.41) ESR1ESR2KMT2AKDM4ETDP1
SCHEMBL25729259 0.74 CASP1 (0.51) ESR1ESR2KMT2AKDM4ETDP1
Ethylene SCHEMBL27629508 0.73 ENPP2 (0.45) KMT2AKDM4ETDP1ENPP2MMP3
SCHEMBL4648586 0.73 KMT2A (0.40) KMT2AKDM4ETDP1L3MBTL1ENPP2
SCHEMBL6758866 0.73 KMT2A (0.44) KMT2AKDM4ETDP1L3MBTL1ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009156623-A1 NOVEL MESOMORPHIC MACROMOLECULAR ORGANIC SEMICONDUCTOR MATERIALS COMMISSARIAT A L´ENERGIE ATOMIQUE (FR) 2009-12-30 WO claimed
WO-2009156623-A1 NOVEL MESOMORPHIC MACROMOLECULAR ORGANIC SEMICONDUCTOR MATERIALS COMMISSARIAT A L´ENERGIE ATOMIQUE (FR) 2009-12-30 WO disclosed