SCHEMBL246959

SCHEMBL246959

N#CCc1ccc(C(F)(F)F)cc1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.48
IDO1 P14902 4/20 0.47
KIF11 P52732 3/20 0.47
MIF P14174 1/20 0.44
DAO P14920 1/20 0.44
MAOB P27338 2/20 0.42
PYCR1 P32322 1/20 0.42
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
NAAA Q02083 1/20 0.41
KMT2A Q03164 1/20 0.40
TSHR P16473 1/20 0.39
SRD5A2 P31213 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2267261 0.94 KIF11 (0.57) TAAR1IDO1KIF11MIFDAO
SCHEMBL10568208 0.94 SRD5A2 (0.46) TAAR1IDO1KIF11MIFDAO
SCHEMBL21029938 0.82 ALDH1A1 (0.37) TAAR1IDO1KIF11MIFDAO
SCHEMBL7594667 0.81 RXRA (0.54) KIF11MAOBNAAA
SCHEMBL2154504 0.80 KMT2A (0.47) KDM4EKMT2A
SCHEMBL4716530 0.78 TAAR1 (0.55) TAAR1IDO1KIF11MIFDAO
SCHEMBL7873873 0.78 PDE2A (0.41) TAAR1ALDH1A1KDM4EKMT2ATSHR
SCHEMBL624792 0.77 IDO1 (0.47) TAAR1IDO1DAOKDM4ENAAA
SCHEMBL4240426 0.77 ESR1 (0.38) ALDH1A1KDM4EKMT2A
SCHEMBL3219286 0.77 PYCR1 (0.55) TAAR1IDO1KIF11MIFMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 504 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119419365-A Multi-element deep eutectic electrolyte of lithium ion battery and preparation method thereof 昆明理工大学 2025-02-11 CN claimed
CN-118961664-A Application of mechanical color-changing pyrenyl derivative in fingerprint extraction 山东理工大学 2024-11-15 CN claimed
CN-118231768-A Electrolyte, sodium ion battery and electric equipment 比亚迪股份有限公司 2024-06-21 CN claimed
CN-118164873-A Preparation method of hole transport material suitable for perovskite solar cell 上海旭励钙钛新能源有限公司 2024-06-11 CN claimed
CN-117317142-A Self-polymerization product modified lithium ion solid-state battery anode based on alkali-initiated in-situ nucleophilic reaction, and preparation method and application thereof 武汉大学 2023-12-29 CN claimed
CN-115417846-B Coumarin-based bimodal high-fluorescence material and synthesis method and application thereof 安徽科技学院 2023-05-26 CN claimed
CN-115417846-A Coumarin-based two-state high-fluorescence material and synthesis method and application thereof 安徽科技学院 2022-12-02 CN claimed
CN-113912517-B Mechanochromic and mechanoluminescent photochromic compound and preparation method and application thereof 河南大学 2022-08-02 CN claimed
CN-113912517-A Mechanochromic and mechanoluminescent photochromic compound and preparation method and application thereof 河南大学 2022-01-11 CN claimed
US-20190284124-A1 FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME ZOGENIX INTERNATIONAL LIMITED (GB) 2019-09-19 US claimed
EP-0394644-A2 Halobenzene derivatives BAYER AG (DE) 1990-10-31 EP claimed
US-4822903-A Fluorinated silica catalyst and preparation of aromatic/aliphatic nitriles in the presence thereof RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1989-04-18 US claimed
US-4438042-A FROM AMIDES, FLUORINATE SILCEOUS CATALYSTS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-03-20 US claimed
US-4436669-A CYANATION, DECARBONYLATION, ACID CATALYSTS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-03-13 US claimed
EP-4293009-B1 FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME ZOGENIX INTERNATIONAL LTD (GB) 2025-06-11 EP disclosed
EP-4067367-B1 OLEANANE CINNAMAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF LUNAN PHARMACEUTICAL GROUP CORP (CN) 2025-05-28 EP disclosed
CN-119874565-A Mono cyano diaryl ethylene preparation method of class compound 常州大学 2025-04-25 CN disclosed
US-4322429-A Isoxazolylbenzamides as insecticides ELI LILLY AND COMPANY (US) 1982-03-30 US disclosed
EP-0048162-A1 Isoxazolylbenzamides ELI LILLY AND COMPANY (US) 1982-03-24 EP disclosed
US-4209621-A TRANQUILIZERS AMERICAN CYANAMID COMPANY (US) 1980-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190284124-A1 FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME FAAH, FAAH2, TPH1 TAAR1 243/4885IDO1 134/4885KIF11 3660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.