Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.55 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.48 |
| ▸ | USP5 | P45974 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5179854 | 0.88 | EPHX2 (0.50) | EPHX2SRD5A1KMT2A | |
| SCHEMBL4244645 | 0.88 | KMT2A (0.62) | EPHX2CYP2C9CYP2J2KMT2A | |
| SCHEMBL4247834 | 0.82 | GRIN2D (0.52) | GAAKMT2A | |
| SCHEMBL4244708 | 0.81 | ALDH1A1 (0.47) | EPHX2KMT2A | |
| SCHEMBL4244550 | 0.81 | EPHX2 (0.54) | EPHX2CYP2C9CYP2J2KMT2A | |
| SCHEMBL4240708 | 0.79 | PARP10 (0.54) | EPHX2SRD5A1 | |
| SCHEMBL4239616 | 0.78 | FAAH (0.61) | KMT2A | |
| SCHEMBL5243542 | 0.75 | SRD5A1 (0.50) | EPHX2SRD5A1KMT2A | |
| SCHEMBL4245344 | 0.75 | GAA (0.48) | GAAKMT2A | |
| SCHEMBL5271411 | 0.75 | EPHX2 (0.59) | EPHX2SRD5A1CYP2C9CYP2J2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170901-A1 | Benzoyl Urea Derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170901-A1 | Benzoyl Urea Derivatives | OPRM1, GRIN2C, GRIN3A | EPHX2 1860/4885SRD5A1 548/4885GAA 3604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.