Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.50 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27900126 | 0.89 | PARP10 (0.67) | PARP10OPRK1SRD5A1KCNH2EPHX2 | |
| SCHEMBL5179858 | 0.89 | PARP10 (0.53) | PARP10OPRK1SRD5A1KCNH2EPHX2 | |
| SCHEMBL4244649 | 0.89 | PARP10 (0.53) | PARP10OPRK1SRD5A1KCNH2EPHX2 | |
| SCHEMBL5243542 | 0.85 | SRD5A1 (0.50) | SRD5A1EPHX2SCD5HTTSRD5A2 | |
| SCHEMBL5271411 | 0.85 | EPHX2 (0.59) | SRD5A1EPHX2SCD5 | |
| SCHEMBL4244711 | 0.82 | DGAT2 (0.44) | EPHX2HTT | |
| SCHEMBL27900111 | 0.82 | OPRK1 (0.68) | OPRK1KCNH2 | |
| SCHEMBL4247838 | 0.81 | PARP10 (0.59) | PARP10GRIN1GRIN2BPARP14 | |
| SCHEMBL4244552 | 0.80 | PARP10 (0.57) | PARP10OPRK1SRD5A1KCNH2EPHX2 | |
| SCHEMBL19610149 | 0.80 | KMT2A (0.46) | PARP10SRD5A1EPHX2HTTSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170901-A1 | Benzoyl Urea Derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170901-A1 | Benzoyl Urea Derivatives | OPRM1, GRIN2C, GRIN3A | PARP10 3694/4885OPRK1 8/4885SRD5A1 548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.