SCHEMBL4244552

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19610351	0.87	FAAH (0.52)	NPC1RAB9AALDH1A1MAPTNR4A2
	SCHEMBL4244649	0.86	PARP10 (0.53)	PARP10OPRK1KCNH2EPHX2CHEK2
	SCHEMBL27670148	0.85	PARP10 (0.54)	PARP10NPC1RAB9AALDH1A1MAPT
	SCHEMBL4244550	0.83	EPHX2 (0.54)	NPC1RAB9AALDH1A1MAPTEPHX2
	SCHEMBL19610193	0.82	SMN1; SMN2 (0.53)	NPC1RAB9AALDH1A1LMNACASP3
	SCHEMBL27900126	0.82	PARP10 (0.67)	PARP10OPRK1KCNH2ALDH1A1EPHX2
	SCHEMBL4246345	0.82	PARP10 (0.64)	PARP10RAB9ANR4A2ADAMTS5NR4A1
	SCHEMBL4251983	0.81	PARP10 (0.62)	PARP10NPC1RAB9ANR4A2CHEK2
	SCHEMBL4240708	0.80	PARP10 (0.54)	PARP10OPRK1KCNH2EPHX2SRD5A1
	SCHEMBL27670250	0.80	PARP10 (0.61)	PARP10NPC1RAB9AEPHX2NR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.