SCHEMBL4240717

SCHEMBL4240717

Cc1ccc(S(=O)(=O)O)cc1CCBr

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.37
ALDH1A1 P00352 9/20 0.37
HSD17B10 Q99714 4/20 0.37
LMNA P02545 3/20 0.35
MAPT P10636 2/20 0.35
GAA P10253 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
HTT P42858 1/20 0.35
S1PR3 Q99500 1/20 0.35
TSHR P16473 2/20 0.34
NT5E P21589 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
CYP2C9 P11712 2/20 0.33
CYP1A2 P05177 1/20 0.33
PHLPP2 Q6ZVD8 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10596213 0.89 ALDH1A1 (0.41) SNCAALDH1A1HSD17B10LMNAMAPT
SCHEMBL10598218 0.86 SNCA (0.39) SNCAALDH1A1HSD17B10LMNAMAPT
SCHEMBL1727437 0.84 SNCA (0.38) SNCAALDH1A1HSD17B10LMNAMAPT
SCHEMBL3339141 0.84 FFAR4 (0.40) SNCAALDH1A1HSD17B10LMNAMAPT
SCHEMBL1804750 0.84 SNCA (0.38) SNCAALDH1A1HSD17B10LMNAMAPT
Ammonia Solution, Strong SCHEMBL27898332 0.83 SNCA (0.37) SNCAALDH1A1HSD17B10LMNAMAPT
SCHEMBL755115 0.83 YAP1 (0.38) SNCAALDH1A1HSD17B10LMNAMAPT
SCHEMBL775810 0.83 TAAR1 (0.38) SNCAALDH1A1HSD17B10LMNAMAPT
SCHEMBL11226081 0.83 SNCA (0.37) SNCAALDH1A1HSD17B10LMNAMAPT
SCHEMBL1607817 0.82 ALDH1A1 (0.41) SNCAALDH1A1HSD17B10LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130137625-A1 Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof SOLARBRE, INC. (US) 2013-05-30 US disclosed
US-8246869-B2 Photo-responsive microencapsulation materials, compositions and methods of use thereof SOLARBRE, INC. (US) 2012-08-21 US disclosed
US-20090202652-A1 Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof SOLARBRE, INC. (US) 2009-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090202652-A1 Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof LIPA, LIPE, CRYAA SNCA 1787/4885ALDH1A1 3388/4885HSD17B10 3865/4885
US-20130137625-A1 Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof LIPA, LIPE, CRYAA SNCA 1787/4885ALDH1A1 3388/4885HSD17B10 3865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.