Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL780171 | 0.86 | ALDH1A1 (0.41) | KDM4ETDP1ALDH1A1RAB9ALMNA | |
| SCHEMBL779057 | 0.80 | HPGD (0.41) | KDM4EALDH1A1RAB9ALMNAHPGD | |
| SCHEMBL2330307 | 0.78 | LMNA (0.51) | KDM4ETDP1ALDH1A1RAB9ALMNA | |
| SCHEMBL1563403 | 0.78 | MAPT (0.40) | KDM4ETDP1ALDH1A1RAB9APOLB | |
| SCHEMBL5402657 | 0.76 | SMN1; SMN2 (0.47) | ALDH1A1LMNAHPGDTSHRKCNH2 | |
| SCHEMBL2281038 | 0.75 | ACP3 (0.46) | LMNAPOLBMEN1KMT2A | |
| SCHEMBL778445 | 0.75 | ALDH1A1 (0.47) | KDM4ETDP1ALDH1A1TSHRPOLB | |
| SCHEMBL788438 | 0.73 | LMNA (0.52) | KDM4ETDP1ALDH1A1RAB9ALMNA | |
| SCHEMBL4112180 | 0.73 | NCEH1 (0.41) | KDM4EALDH1A1RAB9ALMNAHPGD | |
| SCHEMBL11416970 | 0.72 | ANPEP (0.49) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130137625-A1 | Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof | SOLARBRE, INC. (US) | 2013-05-30 | — | — | US | disclosed |
| US-8246869-B2 | Photo-responsive microencapsulation materials, compositions and methods of use thereof | SOLARBRE, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-20090202652-A1 | Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof | SOLARBRE, INC. (US) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090202652-A1 | Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof | LIPA, LIPE, CRYAA | KDM4E 4181/4885TDP1 3305/4885ALDH1A1 3388/4885 |
| US-20130137625-A1 | Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof | LIPA, LIPE, CRYAA | KDM4E 4181/4885TDP1 3305/4885ALDH1A1 3388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.