Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | LDHB | P07195 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13743509 | 0.99 | NPC1 (0.51) | NPC1RAB9ALDHARXFP1HDAC11 | |
| SCHEMBL4566900 | 0.86 | LDHA (0.48) | NPC1RAB9ALDHARXFP1LDHB | |
| SCHEMBL4242831 | 0.86 | LDHA (0.48) | NPC1RAB9ALDHASMN1; SMN2DHODH | |
| SCHEMBL4380936 | 0.85 | LDHA (0.49) | NPC1RAB9ALDHASMN1; SMN2DHODH | |
| SCHEMBL4248057 | 0.85 | LDHA (0.49) | NPC1RAB9ALDHASMN1; SMN2DHODH | |
| SCHEMBL4384687 | 0.85 | LDHA (0.49) | NPC1RAB9ALDHASMN1; SMN2DHODH | |
| SCHEMBL4237844 | 0.84 | LDHA (0.48) | NPC1RAB9ALDHASMN1; SMN2DHODH | |
| SCHEMBL13743520 | 0.84 | LDHA (0.48) | NPC1RAB9ALDHARXFP1LDHB | |
| SCHEMBL4245614 | 0.82 | PGR (0.49) | NPC1RAB9ALDHASMN1; SMN2DHODH | |
| SCHEMBL4246935 | 0.82 | NPC1 (0.47) | NPC1RAB9ARXFP1PTGS1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | FDPS, UMPS, GGPS1 | NPC1 163/4885RAB9A 2428/4885LDHA 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.