Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.33 |
| ▸ | PDE4A | P27815 | 6/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4243417 | 0.82 | FABP4 (0.33) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL4058080 | 0.82 | PDE4A (0.45) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL4241620 | 0.77 | PSEN1 (0.35) | PDE4BPDE4DPDE4APDE4CLMNA | |
| SCHEMBL4515229 | 0.74 | MAOA (0.37) | PDE4BLMNAMAPTNPC1RAB9A | |
| SCHEMBL4235315 | 0.70 | PDE4A (0.31) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL14886437 | 0.64 | MAPT (0.46) | MAPTCYP2C9 | |
| SCHEMBL13693694 | 0.60 | PDE4A (0.41) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL15987332 | 0.60 | NR4A2 (0.42) | LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL24981842 | 0.60 | F2RL1 (0.40) | LMNAMAPTCYP2C9RAB9A | |
| SCHEMBL4230852 | 0.60 | PDE4A (0.45) | PDE4BPDE4DPDE4APDE4CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115874-A2 | NOVEL HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | MATRIX LABORATORIES LTD. (IN) | 2009-09-24 | — | — | WO | disclosed |