Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.49 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 15/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4071820 | 0.91 | P2RX3 (0.49) | P2RX3P2RX2MAPK14 | |
| SCHEMBL4058858 | 0.86 | P2RX3 (0.36) | P2RX3P2RX2MAPK14 | |
| SCHEMBL4245120 | 0.84 | P2RX3 (0.39) | P2RX3P2RX2MAPK14 | |
| SCHEMBL4070477 | 0.80 | TUBB4A (0.44) | P2RX3P2RX2MAPK14 | |
| SCHEMBL4062363 | 0.79 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL4061598 | 0.79 | P2RX3 (0.62) | P2RX3P2RX2 | |
| SCHEMBL4246535 | 0.78 | MAPK14 (0.43) | P2RX3P2RX2MAPK14 | |
| SCHEMBL4060653 | 0.77 | TUBB4A (0.38) | P2RX3P2RX2MAPK14 | |
| SCHEMBL13848091 | 0.77 | IDO1 (0.39) | — | |
| SCHEMBL13848290 | 0.75 | HDAC1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |