Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4071820 | 0.88 | P2RX3 (0.49) | MAPK14P2RX3P2RX2TUBB4ATUBB | |
| SCHEMBL4070477 | 0.86 | TUBB4A (0.44) | MAPK14P2RX3P2RX2TUBB4ATUBB | |
| SCHEMBL4060653 | 0.86 | TUBB4A (0.38) | MAPK14P2RX3P2RX2TUBB4ATUBB | |
| SCHEMBL4245120 | 0.81 | P2RX3 (0.39) | MAPK14P2RX3P2RX2 | |
| SCHEMBL4241628 | 0.78 | P2RX3 (0.49) | MAPK14P2RX3P2RX2 | |
| SCHEMBL4396093 | 0.78 | HSP90AA1 (0.58) | MAPK14HSP90AA1 | |
| SCHEMBL27316536 | 0.78 | P2RX3 (0.53) | P2RX3P2RX2GAA | |
| SCHEMBL4058858 | 0.76 | P2RX3 (0.36) | MAPK14P2RX3P2RX2TUBB4ATUBB | |
| SCHEMBL27840145 | 0.75 | PDE10A (0.46) | MAPK14TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4248092 | 0.73 | POLB (0.45) | P2RX3P2RX2IMPDH2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |