Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4241676 | 0.85 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL4065127 | 0.82 | HSD11B1 (0.58) | HSD11B1CES2 | |
| SCHEMBL4241674 | 0.74 | — | — | |
| SCHEMBL5507886 | 0.73 | HSD11B1 (0.50) | HSD11B1CES2 | |
| SCHEMBL5511640 | 0.70 | HSD11B1 (0.45) | HSD11B1CES2 | |
| SCHEMBL3548948 | 0.69 | HSD11B1 (0.74) | HSD11B1 | |
| SCHEMBL3548392 | 0.68 | HSD11B1 (0.76) | HSD11B1CES2 | |
| SCHEMBL3542808 | 0.67 | HSD11B1 (0.84) | HSD11B1CES2 | |
| SCHEMBL4061157 | 0.67 | HSD11B1 (0.47) | HSD11B1 | |
| SCHEMBL2985349 | 0.67 | HSD11B1 (0.48) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016047-A1 | BIPHENYL AMIDE LACTAM DERIVATIVES AS INHIBITORS OF 11- BETA-HYDROXYSTEROID DEHYDROGENASE 1 | ELI LILLY AND COMPANY (US) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007124337-A1 | BIPHENYL AMIDE LACTAM DERIVATIVES AS INHIBITORS OF 11- BETA-HYDROXYSTEROID DEHYDROGENASE 1 | ELI LILLY AND COMPANY (US) | 2007-11-01 | — | — | WO | disclosed |