Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4241672 | 0.85 | HSD11B1 (0.45) | HSD11B1 | |
| SCHEMBL5507891 | 0.75 | HSD11B1 (0.43) | HSD11B1 | |
| SCHEMBL5511644 | 0.72 | PPARA (0.42) | HSD11B1 | |
| SCHEMBL4696632 | 0.69 | HSD11B1 (0.55) | HSD11B1 | |
| SCHEMBL4696626 | 0.69 | HSD11B1 (0.55) | HSD11B1 | |
| SCHEMBL4065127 | 0.69 | HSD11B1 (0.58) | HSD11B1 | |
| SCHEMBL4697582 | 0.69 | HSD11B1 (0.48) | HSD11B1 | |
| SCHEMBL4697579 | 0.69 | HSD11B1 (0.48) | HSD11B1 | |
| SCHEMBL2988650 | 0.68 | HSD11B1 (0.50) | HSD11B1 | |
| SCHEMBL2993016 | 0.68 | HSD11B1 (0.49) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016047-A1 | BIPHENYL AMIDE LACTAM DERIVATIVES AS INHIBITORS OF 11- BETA-HYDROXYSTEROID DEHYDROGENASE 1 | ELI LILLY AND COMPANY (US) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007124337-A1 | BIPHENYL AMIDE LACTAM DERIVATIVES AS INHIBITORS OF 11- BETA-HYDROXYSTEROID DEHYDROGENASE 1 | ELI LILLY AND COMPANY (US) | 2007-11-01 | — | — | WO | disclosed |