SCHEMBL4241703

SCHEMBL4241703

CCc1cn[c]c(OC)c1CC

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 1/20 0.30
PDE3A Q14432 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9479446 0.74
SCHEMBL8119552 0.71
SCHEMBL3396433 0.68 LMNA (0.36)
SCHEMBL3937380 0.67 NOS3 (0.32)
SCHEMBL456728 0.67 PDE3B (0.31) PDE3BPDE3A
SCHEMBL7129083 0.67 DHFR (0.36)
SCHEMBL4241705 0.65 PTGS2 (0.31) PDE3BPDE3A
SCHEMBL1674656 0.63
SCHEMBL4067084 0.61
SCHEMBL8127077 0.60 HMGCR (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009122148-A1 FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS PI3K KINASE INHIBITORS UCB PHARMA S.A. (BE) 2009-10-08 WO disclosed