Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560084 | 0.82 | CYP3A4 (0.42) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL21102318 | 0.80 | SIGMAR1 (0.47) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL15274890 | 0.80 | SIGMAR1 (0.47) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL49570 | 0.80 | SIGMAR1 (0.47) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL944030 | 0.78 | SIGMAR1 (0.46) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7053823 | 0.78 | SIGMAR1 (0.46) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13170477 | 0.76 | SIGMAR1 (0.44) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16864159 | 0.76 | GABRA1 (0.46) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL722841 | 0.74 | GABRA1 (0.47) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL442008 | 0.73 | TSHR (0.43) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127815-A1 | AMINOALYL-IMIDAZOTETRAZINES FOR TREATMENT OF CANCER | THE UNIVERSITY OF BRADFORD (GB) | 2009-10-22 | — | — | WO | claimed |
| CN-109289048-B | Tumor vascular blocking synergistic phototherapeutic reagent and synthesis method and application thereof | 南京工业大学 | 2021-05-25 | — | — | CN | disclosed |
| WO-2009127815-A1 | AMINOALYL-IMIDAZOTETRAZINES FOR TREATMENT OF CANCER | THE UNIVERSITY OF BRADFORD (GB) | 2009-10-22 | — | — | WO | disclosed |
| US-7138539-B2 | Colorant compounds containing copolymerizable vinyl groups | EASTMAN CHEMICAL COMPANY (US) | 2006-11-21 | — | — | US | disclosed |
| US-7060829-B2 | Colorant compounds containing copolymerizable vinyl groups | EASTMAN CHEMICAL COMPANY (US) | 2006-06-13 | — | — | US | disclosed |
| US-7030244-B2 | Colorant compounds containing copolymerizable vinyl groups | EASTMAN CHEMICAL COMPANY (US) | 2006-04-18 | — | — | US | disclosed |
| US-20060052469-A1 | Colorant compounds containing copolymerizable vinyl groups | CYR MICHAEL J | 2006-03-09 | — | — | US | disclosed |
| US-6727372-B2 | PHOTOPOLYMERIZATION; ADDITION POLYMERS | EASTMAN CHEMICAL COMPANY | 2004-04-27 | — | — | US | disclosed |
| EP-0581065-B1 | Combination of photosensitive elements for use in radiography | IMATION CORP (US) | 1999-10-20 | — | — | EP | disclosed |
| EP-0661592-B1 | Radiographic assembly for chest examination | IMATION CORP (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5136028-A | Red; colorfastness | CIBA-GEIGY CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |
| US-5070248-A | Green phosphor and uv phosphor | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-12-03 | — | — | US | disclosed |
| US-5024928-A | Containing monomethine cyanine dye and thiazole quartnary salt | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-06-18 | — | — | US | disclosed |
| EP-0428482-A1 | Reactive dyes, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1991-05-22 | — | — | EP | disclosed |
| EP-0412730-A2 | An improved cassette and radiographic film combination | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-02-13 | — | — | EP | disclosed |
| EP-0403874-A1 | Light-sensitive elements for radiographic use and process for the formation of an x-ray image | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0350883-A2 | Combination of photosensitive elements for use in radiography | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-01-17 | — | — | EP | disclosed |
| EP-0345483-A2 | Light-sensitive elements for radiographic use and process for the formation of an X-ray image | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-12-13 | — | — | EP | disclosed |
| EP-0345444-A1 | Light-sensitive non-silver photographic element and process for incorporating hydrophobic compositions into hydrophilic colloid compositions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-12-13 | — | — | EP | disclosed |
| US-4419352-A | ANTIALLERGENS; ANTI SECRETORY AGENTS; MUCUS | FISONS LIMITED (GB) | 1983-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052469-A1 | Colorant compounds containing copolymerizable vinyl groups | ALOX5, ALAD, EED | SIGMAR1 3442/4885GRIN2D 1127/4885GRIN3B 1593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.