Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4238217 | 0.83 | HTT (0.45) | SIGMAR1KDM4EMEN1HTTKMT2A | |
| SCHEMBL4240896 | 0.80 | SIGMAR1 (0.40) | GRIN2BSCN1ASCN8ASIGMAR1KDM4E | |
| SCHEMBL4237283 | 0.80 | SIGMAR1 (0.42) | SIGMAR1KCNH2S1PR1MEN1KMT2A | |
| SCHEMBL4248187 | 0.79 | CCR5 (0.39) | KDM4EACHE | |
| SCHEMBL4237325 | 0.79 | SIGMAR1 (0.42) | GRIN2BSCN1ASCN8ASIGMAR1KDM4E | |
| SCHEMBL4242095 | 0.76 | LMNA (0.42) | SIGMAR1S1PR1KDM4EMEN1KMT2A | |
| SCHEMBL4244048 | 0.74 | GRIN2B (0.37) | GRIN2BHRH3SIGMAR1CYP2D6S1PR1 | |
| SCHEMBL4241459 | 0.73 | ACHE (0.41) | GRIN2BSCN1ASCN8ASIGMAR1MEN1 | |
| SCHEMBL4244052 | 0.73 | CHRM2 (0.39) | GRIN2BOPRM1SIGMAR1ACHE | |
| SCHEMBL4244914 | 0.72 | MEN1 (0.42) | SIGMAR1S1PR1MEN1KMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012116-A1 | Muscarinic Receptor Antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012116-A1 | Muscarinic Receptor Antagonists | CHRM3, CHRM2, CHRM5 | GRIN2B 421/4885SCN1A 2445/4885SCN8A 2278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.