Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1022424 | 0.89 | CHRM2 (0.58) | CHRM2ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30994802 | 0.89 | CHRM2 (0.58) | CHRM2ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27890009 | 0.87 | CHRM2 (0.61) | CHRM2ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL4244724 | 0.83 | CHRM2 (0.58) | CHRM2ALDH1A1KMT2AMEN1 | |
| SCHEMBL2914972 | 0.83 | CHRM2 (0.53) | CHRM2ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10800208 | 0.80 | CHRM2 (0.58) | CHRM2ALDH1A1KMT2AMEN1L3MBTL1 | |
| Sulfuric Acid SCHEMBL20984203 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL11147544 | 0.78 | CHRM2 (0.63) | CHRM2ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL8969682 | 0.78 | CHRM2 (0.63) | CHRM2ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7051503 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940964-A1 | TRIARYLMETHANE DYES | Ciba Holding Inc. (CH) | 2008-07-09 | — | — | EP | disclosed |
| EP-1931428-A2 | OXAZINE DISULFIDE DYES | Ciba Holding Inc. (CH) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007039529-A2 | OXAZINE DISULFIDE DYES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007039528-A1 | TRIARYLMETHANE DYES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-04-12 | — | — | WO | disclosed |