Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR0B1 | P51843 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4241297 | 0.86 | NR0B1 (0.46) | NR0B1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4244260 | 0.86 | KMT2A (0.54) | NR0B1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL28620615 | 0.84 | NR0B1 (0.69) | NR0B1LMNAALOX15PLA2G10PLA2G5 | |
| SCHEMBL4246713 | 0.84 | NR0B1 (0.64) | NR0B1ALOX15PLA2G10PLA2G5 | |
| SCHEMBL28622931 | 0.82 | NR0B1 (0.47) | NR0B1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13744100 | 0.80 | NR0B1 (0.51) | NR0B1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4244324 | 0.77 | ALDH1A1 (0.41) | NR0B1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4241352 | 0.77 | NR0B1 (0.40) | NR0B1ALDH1A1LMNARNASEH1HPGD | |
| SCHEMBL29464991 | 0.76 | NR0B1 (1.00) | NR0B1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13743665 | 0.76 | NR0B1 (0.52) | NR0B1MEN1KMT2ALMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402436-B | Tertiary amino acid derivative, preparation method and application thereof | 安徽农业大学 | 2024-07-12 | — | — | CN | disclosed |
| CN-113402436-A | Trolamine derivatives, preparation method and application thereof | 安徽农业大学 | 2021-09-17 | — | — | CN | disclosed |
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | FDPS, UMPS, GGPS1 | NR0B1 2001/4885ALDH1A1 3119/4885MEN1 2345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.