Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.51 |
| ▸ | STS | P08842 | 8/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CPS1 | P31327 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22491573 | 0.84 | STS (0.56) | PTPN2PTPN1PTPN6STSHPGD | |
| SCHEMBL15566264 | 0.84 | MEN1 (0.54) | PTPN2PTPN1PTPN6STSGPR119 | |
| SCHEMBL15566640 | 0.84 | STS (0.54) | PTPN2PTPN1PTPN6STSGPR119 | |
| SCHEMBL16818362 | 0.83 | STS (0.57) | PTPN2PTPN1PTPN6STSHPGD | |
| SCHEMBL25452815 | 0.82 | STS (0.51) | PTPN2PTPN1PTPN6STSGPR119 | |
| SCHEMBL17495365 | 0.82 | USP30 (0.50) | PTPN2PTPN1PTPN6STSGPR119 | |
| SCHEMBL2960444 | 0.81 | STS (0.56) | PTPN2PTPN1PTPN6STSGPR119 | |
| SCHEMBL17007796 | 0.81 | GPR119 (0.56) | PTPN2PTPN1PTPN6STSGPR119 | |
| SCHEMBL20971852 | 0.81 | STS (0.56) | PTPN2PTPN1PTPN6STSGPR119 | |
| SCHEMBL2957540 | 0.81 | STS (0.50) | PTPN2PTPN1PTPN6STSGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491735-B2 | Chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2009-02-17 | — | — | US | disclosed |
| EP-1708703-A4 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2008-04-09 | — | — | EP | disclosed |
| EP-1708703-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-10-11 | — | — | EP | disclosed |
| US-20050277670-A1 | Chemokine receptor binding compounds | ANORMED INC. | 2005-12-15 | — | — | US | disclosed |
| WO-2005059107-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277670-A1 | Chemokine receptor binding compounds | CCR5, CXCR3, CCL5 | PTPN2 1136/4885PTPN1 1609/4885PTPN6 1599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.