SCHEMBL4245772

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4246703	0.91	OPRM1 (0.50)	OPRM1OPRK1HTR1ADRD2DRD4
	SCHEMBL4241368	0.90	OPRM1 (0.49)	OPRM1OPRK1HRH3AOC3HTR1A
	SCHEMBL4244857	0.87	SMN1; SMN2 (0.48)	OPRM1OPRK1PPARGPARP1L3MBTL1
	SCHEMBL4240910	0.85	MAPT (0.42)	OPRM1OPRK1HTR1ADRD2DRD4
	SCHEMBL4245098	0.83	OPRM1 (0.45)	OPRM1OPRK1HTR1ADRD2DRD4
	SCHEMBL4248577	0.83	MAPT (0.45)	OPRM1OPRK1HTR1ADRD2DRD4
	SCHEMBL4246582	0.83	DRD3 (0.54)	OPRM1OPRK1HTR1ADRD2DRD4
	SCHEMBL4245287	0.83	MAPT (0.42)	OPRM1OPRK1HTR1ADRD2DRD4
	SCHEMBL4400914	0.83	DRD2 (0.52)	OPRM1OPRK1HTR1ADRD2DRD4
	SCHEMBL28781388	0.82	MAPK1 (0.43)	OPRM1OPRK1HTR1ADRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.