Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031668 | 0.87 | HSD17B10 (0.53) | KDM4ELMNAHSD17B10CYP1A2SCN10A | |
| SCHEMBL4230805 | 0.78 | ALDH1A1 (0.56) | KDM4EHSD17B10ALDH1A1HPGDCYP2A6 | |
| SCHEMBL18776138 | 0.77 | KDM4E (0.53) | KDM4ELMNAHSD17B10CYP1A2SCN10A | |
| SCHEMBL5031699 | 0.77 | KDM4E (0.61) | KDM4ECYP1A2ALDH1A1CYP2A6KMT2A | |
| SCHEMBL6985209 | 0.77 | KDM4E (0.42) | KDM4ELMNAHSD17B10ALDH1A1KIF11 | |
| SCHEMBL798790 | 0.76 | SCN10A (0.69) | KDM4ELMNAHSD17B10CYP1A2SCN10A | |
| SCHEMBL890080 | 0.76 | CYP1A2 (0.75) | KDM4ELMNAHSD17B10CYP1A2SCN10A | |
| SCHEMBL12248517 | 0.75 | PLAU (0.56) | ALDH1A1CYP2A6MEN1KMT2AKIF11 | |
| SCHEMBL7245711 | 0.75 | CYP2A6 (0.44) | KDM4ELMNAALDH1A1HPGDCYP2A6 | |
| SCHEMBL14197238 | 0.75 | KDM4E (0.57) | KDM4ELMNAHSD17B10CYP1A2SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048252-A1 | THIAZOLONES FOR USE AS PI3 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION | 2009-02-19 | — | — | US | disclosed |
| US-20070249599-A1 | Novel Chemical Compounds | DUFFY KEVIN J | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249599-A1 | Novel Chemical Compounds | HIPK3, HIPK1, HIPK4 | KDM4E 2565/4885LMNA 1240/4885HSD17B10 920/4885 |
| US-20090048252-A1 | THIAZOLONES FOR USE AS PI3 KINASE INHIBITORS | PIK3CA, BTK, PI4KA | KDM4E 3686/4885LMNA 4788/4885HSD17B10 3245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.