Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.32 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065989 | 0.89 | POLB (0.39) | POLBHSD17B10MAPTHPGDTSHR | |
| SCHEMBL13848381 | 0.82 | RXRA (0.41) | KMT2A | |
| SCHEMBL4069820 | 0.77 | HSP90AA1 (0.46) | — | |
| SCHEMBL4246535 | 0.73 | MAPK14 (0.43) | P2RX3P2RX2LMNAGAAIMPDH2 | |
| SCHEMBL4064309 | 0.73 | NOTUM (0.41) | MAPTHPGDLMNA | |
| SCHEMBL28166742 | 0.72 | HPGD (0.49) | POLBHSD17B10MAPTHPGDTSHR | |
| SCHEMBL4241628 | 0.72 | P2RX3 (0.49) | P2RX3P2RX2 | |
| SCHEMBL4058858 | 0.70 | P2RX3 (0.36) | HSD17B10MAPTHPGDP2RX3P2RX2 | |
| SCHEMBL4071820 | 0.69 | P2RX3 (0.49) | P2RX3P2RX2 | |
| SCHEMBL4243902 | 0.68 | IMPDH2 (0.56) | AAK1IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |