Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN1 | Q16512 | 5/20 | 0.55 |
| ▸ | PKN2 | Q16513 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | RHEB | Q15382 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | BRAF | P15056 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CBFB | Q13951 | 2/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2105253 | 0.86 | NPC1 (0.57) | PKN1PKN2KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11378451 | 0.85 | NPC1 (0.56) | PKN1PKN2KDM4EALDH1A1HPGD | |
| SCHEMBL19970793 | 0.83 | NPBWR1 (0.56) | — | |
| SCHEMBL4245678 | 0.83 | ALDH1A1 (0.62) | PKN1PKN2KDM4EALDH1A1HPGD | |
| Ridinilazole SCHEMBL413723 | 0.80 | ALDH1A1 (0.66) | PKN1PKN2KDM4EALDH1A1HPGD | |
| Ridinilazole SCHEMBL29379856 | 0.80 | ALDH1A1 (0.66) | PKN1PKN2KDM4EALDH1A1HPGD | |
| SCHEMBL124236 | 0.77 | NPBWR1 (0.49) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL16498509 | 0.77 | KDM4E (0.57) | PKN1PKN2KDM4EALDH1A1HPGD | |
| SCHEMBL7164761 | 0.76 | RHEB (0.69) | PKN1PKN2KDM4EALDH1A1HPGD | |
| SCHEMBL30343722 | 0.76 | KDM4E (0.60) | PKN1PKN2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048252-A1 | THIAZOLONES FOR USE AS PI3 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION | 2009-02-19 | — | — | US | disclosed |
| US-20070249599-A1 | Novel Chemical Compounds | DUFFY KEVIN J | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249599-A1 | Novel Chemical Compounds | HIPK3, HIPK1, HIPK4 | PKN1 504/4885PKN2 974/4885KDM4E 2565/4885 |
| US-20090048252-A1 | THIAZOLONES FOR USE AS PI3 KINASE INHIBITORS | PIK3CA, BTK, PI4KA | PKN1 983/4885PKN2 875/4885KDM4E 3686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.