Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 2/20 | 0.39 |
| ▸ | CHUK | O15111 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10827629 | 0.83 | TSHR (0.44) | AHRTSHRCYP3A4TDO2MAP4K4 | |
| SCHEMBL4787759 | 0.82 | AHR (0.42) | AHRTSHRTDO2MAP4K4CYP1A2 | |
| SCHEMBL10818104 | 0.81 | ALDH1A1 (0.48) | AHRTSHRCYP3A4TP53HTR2B | |
| SCHEMBL4448755 | 0.77 | AHR (0.68) | AHRTSHRCYP1A2TP53ALDH1A1 | |
| SCHEMBL4248838 | 0.75 | AHR (0.65) | AHRTSHRCYP3A4MAP4K4CYP1A2 | |
| SCHEMBL29407089 | 0.74 | CYP3A4 (0.45) | AHRCYP3A4TDO2MAP4K4CYP1A2 | |
| SCHEMBL5795293 | 0.74 | ALDH1A1 (0.54) | AHRTSHRCYP3A4KCNH2NPC1 | |
| SCHEMBL5952748 | 0.74 | AHR (0.42) | AHRTSHRCYP3A4TDO2MAP4K4 | |
| SCHEMBL9600526 | 0.74 | DPP4 (0.47) | AHRCYP3A4 | |
| SCHEMBL1577931 | 0.73 | TSHR (0.54) | AHRTSHRCYP3A4TDO2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9132411-B2 | Strategies, linkers and coordination polymers for high-performance sorbents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2015-09-15 | — | — | US | disclosed |
| US-20130237411-A1 | Novel Strategies, Linkers and Coordination Polymers for High-Performance Sorbents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2013-09-12 | — | — | US | disclosed |
| US-8383545-B2 | Strategies, linkers and coordination polymers for high-performance sorbents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2013-02-26 | — | — | US | disclosed |
| US-20090062498-A1 | NOVEL STRATEGIES, LINKERS AND COORDINATION POLYMERS FOR HIGH-PERFORMANCE SORBENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-03-05 | — | — | US | disclosed |
| WO-2009029838-A1 | NOVEL STRATEGIES, LINKERS AND COORDINATION POLYMERS FOR HIGH-PERFORMANCE SORBENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237411-A1 | Novel Strategies, Linkers and Coordination Polymers for High-Performance Sorbents | ILK, TIMCC, EPCAM | AHR 3157/4885TSHR 4534/4885CYP3A4 3289/4885 |
| US-20090062498-A1 | NOVEL STRATEGIES, LINKERS AND COORDINATION POLYMERS FOR HIGH-PERFORMANCE SORBENTS | ILK, TIMCC, EPCAM | AHR 3157/4885TSHR 4534/4885CYP3A4 3289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.