Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.39 |
| ▸ | GCGR | P47871 | 2/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871472 | 0.90 | PTGS2 (0.42) | NPC1RAB9AMEN1KMT2AMAPK14 | |
| SCHEMBL6120928 | 0.85 | NPC1 (0.41) | AHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4687459 | 0.85 | CYP2A6 (0.43) | MEN1KMT2AMAP4K4SMN1; SMN2HSD17B10 | |
| SCHEMBL4247286 | 0.82 | AHR (0.47) | AHRNPC1RAB9AMKNK1MKNK2 | |
| SCHEMBL22616582 | 0.78 | TAAR1 (0.47) | MEN1KMT2AMAP4K4 | |
| SCHEMBL3950704 | 0.74 | ALDH1A1 (0.45) | AHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL1951099 | 0.73 | CYP3A4 (0.58) | TP53TSHR | |
| SCHEMBL3651531 | 0.73 | PLA2G7 (0.44) | NPC1RAB9AMEN1KMT2AMAPK14 | |
| Bromide SCHEMBL10949048 | 0.71 | ALDH1A1 (0.55) | TP53TSHR | |
| SCHEMBL4749166 | 0.70 | TSHR (0.47) | AHRNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122555-A1 | 2-NITRO-5-FLUORO-3',4'-DICHLOROBIPHENYL AND METHOD FOR THE PRODUCTION THEREOF | SALTIGO GMBH (DE) | 2008-10-16 | — | — | WO | disclosed |