SCHEMBL4247494

SCHEMBL4247494

C/C=C\C=C/CC/C=C/C=C/C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.60
CNR2 P34972 9/20 0.53
CNR1 P21554 7/20 0.53
PPARG P37231 2/20 0.53
PPARD Q03181 2/20 0.53
TRPA1 O75762 1/20 0.46
TRPV1 Q8NER1 1/20 0.46
TBXAS1 P24557 2/20 0.40
SOAT1 P35610 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8347693 1.00 PPARA (0.60) PPARACNR2CNR1PPARGPPARD
SCHEMBL4920953 1.00 PPARA (0.60) PPARACNR2CNR1PPARGPPARD
SCHEMBL4245971 1.00 PPARA (0.60) PPARACNR2CNR1PPARGPPARD
SCHEMBL8347698 1.00 PPARA (0.60) PPARACNR2CNR1PPARGPPARD
SCHEMBL669179 0.91 CNR2 (0.50) PPARACNR2CNR1PPARGPPARD
SCHEMBL3308337 0.91 PPARA (0.60) PPARACNR2CNR1PPARGPPARD
SCHEMBL669177 0.91 CNR2 (0.50) PPARACNR2CNR1PPARGPPARD
SCHEMBL669178 0.91 CNR2 (0.50) PPARACNR2CNR1PPARGPPARD
SCHEMBL3308333 0.91 PPARA (0.60) PPARACNR2CNR1PPARGPPARD
SCHEMBL10300846 0.91 CNR2 (0.50) PPARACNR2CNR1PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200078333-A1 Healthier Aging in Domesticated Animals POSTREL RICHARD (US) 2020-03-12 US claimed
US-20190029993-A1 QUALITY OF LIFE EXTENSION THERAPIES RELATING TO AGING, FOOD ALLERGIES, PAIN AND REDUCED VIGOR BY MANAGING MOLECULAR, CELLULAR AND SUBCELLULAR BIOCHEMICAL REQUIREMENTS OF MITOCHONDRIA AND OTHER ORGANELLE PROCESSES REVIGORON LLC 2019-01-31 US claimed
US-20190030044-A1 HUMAN LIFE EXTENSION THERAPY THROUGH MOLECULAR, CELLULAR AND SUBCELLULAR MANAGEMENT OF BIOCHEMICAL REQUIREMENTS OF MITOCHONDRIA AND OF OTHER ORGANELLE PROCESSES ASSOCIATED WITH THE ADVENT OF DISEASE AND/OR AGING POSTREL RICHARD (US) 2019-01-31 US claimed
WO-2018118197-A1 HEALTHIER AGING IN DOMESTICATED ANIMALS POSTREL RICHARD (US) 2018-06-28 WO claimed
US-20230404942-A1 Life Extension and Quality of Life Improvement for Humans POSTREL RICHARD (US) 2023-12-21 US disclosed
US-20230114740-A1 Life Extension and Quality of Life Improvement for Humans and Other Mammals POSTREL RICHARD (US) 2023-04-13 US disclosed
US-20220175694-A1 Anti-Aging Therapy for Canines and Other Domesticated Animals POSTREL RICHARD (US) 2022-06-09 US disclosed
US-20210228502-A1 Anti-Aging Therapy for Canines and Other Domesticated Animals REVIGORON LLC 2021-07-29 US disclosed
US-20200078333-A1 Healthier Aging in Domesticated Animals POSTREL RICHARD (US) 2020-03-12 US disclosed
US-20190314325-A1 Process and Method to Accelerate Cellular Regeneration, Healing and Wound Management POSTREL RICHARD (US) 2019-10-17 US disclosed
US-20190030044-A1 HUMAN LIFE EXTENSION THERAPY THROUGH MOLECULAR, CELLULAR AND SUBCELLULAR MANAGEMENT OF BIOCHEMICAL REQUIREMENTS OF MITOCHONDRIA AND OF OTHER ORGANELLE PROCESSES ASSOCIATED WITH THE ADVENT OF DISEASE AND/OR AGING POSTREL RICHARD (US) 2019-01-31 US disclosed
US-20190029993-A1 QUALITY OF LIFE EXTENSION THERAPIES RELATING TO AGING, FOOD ALLERGIES, PAIN AND REDUCED VIGOR BY MANAGING MOLECULAR, CELLULAR AND SUBCELLULAR BIOCHEMICAL REQUIREMENTS OF MITOCHONDRIA AND OTHER ORGANELLE PROCESSES REVIGORON LLC 2019-01-31 US disclosed
WO-2018118197-A1 HEALTHIER AGING IN DOMESTICATED ANIMALS POSTREL RICHARD (US) 2018-06-28 WO disclosed
US-20090054526-A1 INHIBITORS OF ANOREXIC LIPID HYDROLYSIS FOR THE TREATMENT OF EATING DISORDERS UNIVERSITY OF COPENHAGEN (DK) 2009-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054526-A1 INHIBITORS OF ANOREXIC LIPID HYDROLYSIS FOR THE TREATMENT OF EATING DISORDERS LIPE, PNLIP, FAAH2 PPARA 933/4885CNR2 460/4885CNR1 674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.