Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.44 |
| ▸ | HSD11B2 | P80365 | 4/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9589205 | 0.84 | HSD11B1 (0.47) | HSD11B1HSD11B2CNR1ALDH1A1KDM4E | |
| SCHEMBL1046455 | 0.84 | ALDH1A1 (0.60) | HSD11B1HSD11B2CNR1ALDH1A1KDM4E | |
| SCHEMBL12301773 | 0.84 | HSD11B1 (0.44) | HSD11B1HSD11B2CNR1ALDH1A1KDM4E | |
| SCHEMBL29195871 | 0.82 | ALDH1A1 (0.58) | HSD11B1HSD11B2CNR1ALDH1A1KDM4E | |
| SCHEMBL28821566 | 0.80 | TDP1 (0.49) | ALDH1A1KDM4EHSD17B10MAPTKMT2A | |
| SCHEMBL4423002 | 0.77 | PPARA (0.59) | CNR1ALDH1A1MAPTRAB9A | |
| SCHEMBL16585163 | 0.77 | KMT2A (0.46) | ALDH1A1KDM4ELMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL2737124 | 0.76 | LMNA (0.43) | ALDH1A1LMNASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL2668311 | 0.76 | ALDH1A1 (0.73) | ALDH1A1KDM4EHSD17B10L3MBTL1MAPT | |
| SCHEMBL28343305 | 0.76 | LMNA (0.46) | ALDH1A1KDM4EHSD17B10LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090196838-A1 | Arthropod Repellent Pharmacophore Models, Compounds Identified as Fitting the Pharmacophore Models, and Methods of Making and Using Thereof | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND | 2009-08-06 | — | — | US | claimed |
| EP-1689229-A1 | ARTHROPOD REPELLENT PHARMACOPHORE MODELS, COMPOUNDS IDENTIFIED AS FITTING THE PHARMACOPHORE MODELS, AND METHODS OF MAKING AND USING THEREOF | United States Army Medical Research and Materiel Command (US) | 2006-08-16 | — | — | EP | claimed |
| WO-2005046329-A1 | ARTHROPOD REPELLENT PHARMACOPHORE MODELS, COMPOUNDS IDENTIFIED AS FITTING THE PHARMACOPHORE MODELS, AND METHODS OF MAKING AND USING THEREOF | UNITED STATES MEDICAL RESEARCH AND MATERIEL COMMAND (US) | 2005-05-26 | — | — | WO | claimed |
| US-20050100575-A1 | Arthropod repellent pharmacophore models, compounds identified as fitting the pharmacophore models, and methods of making and using thereof | ARMY, UNITED STATES | 2005-05-12 | — | — | US | claimed |
| US-20090196838-A1 | Arthropod Repellent Pharmacophore Models, Compounds Identified as Fitting the Pharmacophore Models, and Methods of Making and Using Thereof | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND | 2009-08-06 | — | — | US | disclosed |
| US-20090196838-A1 | Arthropod Repellent Pharmacophore Models, Compounds Identified as Fitting the Pharmacophore Models, and Methods of Making and Using Thereof | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND | 2009-08-06 | — | — | US | disclosed |
| US-20090196838-A1 | Arthropod Repellent Pharmacophore Models, Compounds Identified as Fitting the Pharmacophore Models, and Methods of Making and Using Thereof | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND | 2009-08-06 | — | — | US | disclosed |
| US-7498331-B2 | Arthropod repellent pharmacophore models, compounds identified as fitting the pharmacophore models, and methods of making and using thereof | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498331-B2 | Arthropod repellent pharmacophore models, compounds identified as fitting the pharmacophore models, and methods of making and using thereof | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2009-03-03 | — | — | US | disclosed |
| EP-1689229-A1 | ARTHROPOD REPELLENT PHARMACOPHORE MODELS, COMPOUNDS IDENTIFIED AS FITTING THE PHARMACOPHORE MODELS, AND METHODS OF MAKING AND USING THEREOF | United States Army Medical Research and Materiel Command (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005046329-A1 | ARTHROPOD REPELLENT PHARMACOPHORE MODELS, COMPOUNDS IDENTIFIED AS FITTING THE PHARMACOPHORE MODELS, AND METHODS OF MAKING AND USING THEREOF | UNITED STATES MEDICAL RESEARCH AND MATERIEL COMMAND (US) | 2005-05-26 | — | — | WO | disclosed |
| US-20050100575-A1 | Arthropod repellent pharmacophore models, compounds identified as fitting the pharmacophore models, and methods of making and using thereof | ARMY, UNITED STATES | 2005-05-12 | — | — | US | disclosed |
| US-4339372-A | Process of preparing stabilized polychloroprene latex | DISTUGIL (FR) | 1982-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050100575-A1 | Arthropod repellent pharmacophore models, compounds identified as fitting the pharmacophore models, and methods of making and using thereof | TYR, ABCG2, CHIA | HSD11B1 1575/4885HSD11B2 1881/4885CNR1 224/4885 |
| US-20090196838-A1 | Arthropod Repellent Pharmacophore Models, Compounds Identified as Fitting the Pharmacophore Models, and Methods of Making and Using Thereof | TYR, ABCG2, CHIA | HSD11B1 1575/4885HSD11B2 1881/4885CNR1 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.