Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28397003 | 0.84 | CASP3 (0.40) | LMNATDP1L3MBTL1MAPK1BCAT2 | |
| SCHEMBL28343384 | 0.83 | KDM4E (0.47) | LMNATDP1L3MBTL1MAPK1KDM4E | |
| SCHEMBL28340902 | 0.83 | LMNA (0.46) | LMNATDP1L3MBTL1MAPK1KDM4E | |
| SCHEMBL27335556 | 0.81 | L3MBTL1 (0.49) | LMNATDP1L3MBTL1MAPK1KDM4E | |
| SCHEMBL4037713 | 0.79 | ALDH1A1 (0.54) | LMNATDP1L3MBTL1MAPK1KDM4E | |
| SCHEMBL28821566 | 0.77 | TDP1 (0.49) | TDP1MAPK1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL28343385 | 0.77 | KDM4E (0.48) | LMNATDP1L3MBTL1MAPK1KDM4E | |
| SCHEMBL8017279 | 0.76 | HTR7 (0.46) | LMNATDP1L3MBTL1MAPK1KDM4E | |
| SCHEMBL4247858 | 0.76 | HSD11B1 (0.44) | LMNATDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL27515199 | 0.74 | HTR7 (0.44) | LMNATDP1L3MBTL1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117965536-A | Oligonucleotide compositions and methods thereof | 波涛生命科学有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-112384517-B | Heteroaryl compounds and uses thereof | 新旭生技股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-115667207-A | Cationic lipids based on phenolic acid lipids | 翻译生物公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-114945572-A | HBF pharmacological inducing compounds for the treatment of sickle cell anemia and beta-thalassemia | 刘扶东 | 2022-08-26 | — | — | CN | disclosed |
| CN-108884054-B | Compounds for the treatment of proliferative diseases | 儿童医学中心公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-114751920-A | Antitumor compounds | 法马马有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114736219-A | Antitumor compounds | 法马马有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114746095-A | HCK as therapeutic target of MYD88 mutant disease | 达纳-法伯癌症研究所有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-113398126-A | Use of 4' -deferthionin analogues | 佛罗里达大学研究基金会 | 2021-09-17 | — | — | CN | disclosed |
| CN-113195720-A | Enzymatic RNA synthesis | 哈佛大学的校长及成员们 | 2021-07-30 | — | — | CN | disclosed |
| CN-107835871-B | Methods and compositions for peptide cyclization and protease treatment | 豪夫迈·罗氏有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-112812143-A | Triterpene saponin analogues | 佐剂技术公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-107074806-B | HSP70 modulators and methods of making and using the same | 纪念斯隆-凯特琳癌症中心 | 2021-04-23 | — | — | CN | disclosed |
| CN-107522664-B | Amino acid derivatives functionalized at the N-terminus capable of forming drug-encapsulated microspheres | 麻省理工学院 | 2021-03-16 | — | — | CN | disclosed |
| CN-112384517-A | Heteroaryl compounds and uses thereof | 新旭生技股份有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-108778289-B | Triterpene saponin analogues | 佐剂技术公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-110730666-A | Triterpene saponin analogues | 佐剂技术公司 | 2020-01-24 | — | — | CN | disclosed |
| CN-109136974-B | C (sp) -containing2) Process for producing (E) -N bond compound | 中国科学院上海有机化学研究所 | 2019-12-31 | — | — | CN | disclosed |
| CN-110621678-A | Antitumor compounds | 法马马有限公司 | 2019-12-27 | — | — | CN | disclosed |
| CN-110582282-A | Triterpene saponin analogues | 佐剂技术公司 | 2019-12-17 | — | — | CN | disclosed |