Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29270413 | 0.83 | TSHR (0.44) | BBOX1ALDH1A1TSHRDNM1HTT | |
| SCHEMBL18690259 | 0.81 | BBOX1 (0.40) | BBOX1ALDH1A1TSHR | |
| SCHEMBL9408649 | 0.79 | HTT (0.50) | BBOX1ALDH1A1TSHRDNM1HTT | |
| SCHEMBL9408557 | 0.78 | ALDH1A1 (0.48) | BBOX1ALDH1A1TSHRDNM1 | |
| SCHEMBL902258 | 0.78 | ACHE (0.46) | BBOX1ALDH1A1TSHRKMT2AACHE | |
| Hydrochloric Acid SCHEMBL10384120 | 0.76 | HTT (0.52) | BBOX1DNM1HTTKMT2AHSP90AA1 | |
| Hydrochloric Acid SCHEMBL10383871 | 0.76 | HTT (0.52) | BBOX1DNM1HTTKMT2AHSP90AA1 | |
| SCHEMBL902256 | 0.76 | ALDH1A1 (0.44) | BBOX1ALDH1A1TSHRACHE | |
| Hydrochloric Acid SCHEMBL422093 | 0.76 | ACHE (0.44) | BBOX1ALDH1A1TSHRACHEAPOBEC3A | |
| SCHEMBL28854167 | 0.76 | ALDH1A1 (0.50) | BBOX1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724290-B1 | LIQUID COMPOSITION CONTAINING NO SOLVENT | NISSHIN SPINNING (JP) | 2009-07-08 | — | — | EP | disclosed |
| US-20070194275-A1 | Liquid composition containing no solvent | NISSHINBO INDUSTRIES, INC. (JP) | 2007-08-23 | — | — | US | disclosed |
| EP-1724290-A1 | LIQUID COMPOSITION CONTAINING NO SOLVENT | Nisshinbo Industries, Inc. (JP) | 2006-11-22 | — | — | EP | disclosed |