SCHEMBL4248432

SCHEMBL4248432

O=C(O)C(Cc1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
CYP1A2 P05177 4/20 0.54
CYP2C19 P33261 3/20 0.54
CYP2C9 P11712 1/20 0.54
AKR1B1 P15121 1/20 0.48
CYP3A4 P08684 1/20 0.45
RECQL P46063 1/20 0.45
FDPS P14324 1/20 0.44
MAPK1 P28482 1/20 0.44
KIF11 P52732 1/20 0.44
CES1 P23141 2/20 0.43
CES2 O00748 1/20 0.43
KCNA5 P22460 1/20 0.42
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
OPRM1 P35372 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11611268 0.98 SMN1; SMN2 (0.53) HIF1ASMN1; SMN2CYP1A2CYP2C19CYP2C9
SCHEMBL2291376 0.88 SMN1; SMN2 (0.48) HIF1ASMN1; SMN2CYP1A2CYP2C19CYP2C9
SCHEMBL1492533 0.83 SMN1; SMN2 (0.52) HIF1ASMN1; SMN2CYP1A2CYP2C19CYP2C9
SCHEMBL11611265 0.83 CYP1A2 (0.50) HIF1ASMN1; SMN2CYP1A2CYP2C19CYP2C9
SCHEMBL14297778 0.82 KIF11 (0.46) HIF1ASMN1; SMN2CYP1A2CYP2C19CYP2C9
SCHEMBL20546662 0.82 CYP1A2 (0.48) HIF1ASMN1; SMN2CYP1A2CYP2C19CYP2C9
SCHEMBL1234755 0.78 CYP1A2 (0.59) HIF1ASMN1; SMN2CYP1A2CYP2C19CYP2C9
SCHEMBL28709945 0.78 CYP2C9 (0.54) HIF1ASMN1; SMN2CYP1A2CYP2C19CYP2C9
SCHEMBL329090 0.78 HIF1A (0.55) HIF1ASMN1; SMN2CYP1A2CYP2C19CYP2C9
SCHEMBL5481737 0.77 MMP8 (0.56) HIF1ASMN1; SMN2CYP1A2CYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039755-B Heat dissipation type carbon fiber battery rear cover and preparation method thereof 广东纵胜新材料股份有限公司 2025-04-11 CN claimed
CN-119039755-A Heat dissipation type carbon fiber battery rear cover and preparation method thereof 广东纵胜新材料股份有限公司 2024-11-29 CN claimed
CN-119039755-B Heat dissipation type carbon fiber battery rear cover and preparation method thereof 广东纵胜新材料股份有限公司 2025-04-11 CN disclosed
US-20250051477-A1 ANTI-MUSK ANTIBODIES FOR USE IN TREATING NEUROMUSCULAR DISORDERS argenx BV (BE) 2025-02-13 US disclosed
CN-119118904-A Preparation method of N-hydroxyphthalimide ester containing quaternary carbon center 南京工业大学 2024-12-13 CN disclosed
EP-4469085-A2 ANTI-MUSK ANTIBODIES FOR USE IN TREATING NEUROMUSCULAR DISORDERS Argenx BV (BE) 2024-12-04 EP disclosed
CN-119039755-A Heat dissipation type carbon fiber battery rear cover and preparation method thereof 广东纵胜新材料股份有限公司 2024-11-29 CN disclosed
CN-119013308-A Anti-MuSK antibodies for the treatment of neuromuscular disorders 阿根思有限公司 2024-11-22 CN disclosed
US-20240374563-A1 ANTICHOLINERGIC COMPOUNDS FOR USE IN TREATING NEUROMUSCULAR DISORDERS UNIVERSITY OF MONTRÉAL (CA) 2024-11-14 US disclosed
CN-117447466-A Oxazole compound and preparation method and application thereof 中国科学院上海药物研究所 2024-01-26 CN disclosed
WO-2023147489-A2 ANTI-MUSK ANTIBODIES FOR USE IN TREATING NEUROMUSCULAR DISORDERS argenx BV (BE) 2023-08-03 WO disclosed
CN-1251037-A Triarylmethane compounds for sickle cell disease HARVARD COLLEGE (US) 2000-04-19 CN disclosed
US-6028103-A Triaryl methane compounds and analogues thereof useful for the treatment or prevention of sickle cell disease or diseases characterized by abnormal cell proliferation CHILDREN'S MEDICAL CENTER CORPORATION (US) 2000-02-22 US disclosed
WO-1999026624-A1 USE OF SUBSTITUTED DIPHENYL INDANONE, INDANE AND INDOLE COMPOUNDS FOR THE TREATMENT OR PREVENTION OF SICKLE CELL DISEASE, INFLAMMATORY DISEASES CHARACTERIZED BY ABNORMAL CELL PROLIFERATION, DIARRHE AND SCOURS CHILDREN'S MEDICAL CENTER CORPORATION (US) 1999-06-03 WO disclosed
WO-1999026611-A1 SUBSTITUTED DIPHENYL INDANONE, INDANE AND INDOLE COMPOUNDS AND ANALOGUES THEREOF USEFUL FOR THE TREATMENT OR PREVENTION OF DISEASES CHARACTERIZED BY ABNORMAL CELL PROLIFERATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1999-06-03 WO disclosed
EP-0918514-A1 TRIARYL METHANE COMPOUNDS FOR SICKLE CELL DISEASE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1999-06-02 EP disclosed
WO-1997034589-A1 TRIARYL METHANE COMPOUNDS FOR SICKLE CELL DISEASE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1997-09-25 WO disclosed
US-4824532-A Process for the electrochemical synthesis of carboxylic acids SOCIETE NATIONALE INDUSTRIELLE ET AEROSPATIALE DES POUDRES ET (FR) 1989-04-25 US disclosed
US-4290959-A Preparation of propylene oxide HALCON RESEARCH AND DEVELOPMENT CORP. (US) 1981-09-22 US disclosed
US-4116963-A ANTIDIARRHEAL, CENTRAL NERVOUS SYSTEM PROPERTIES G.D. SEARLE & CO. (US) 1978-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240374563-A1 ANTICHOLINERGIC COMPOUNDS FOR USE IN TREATING NEUROMUSCULAR DISORDERS CHRNA6, CHRNA5, CHRNA10 HIF1A 4654/4885SMN1; SMN2 29/4885CYP1A2 3666/4885
US-20250051477-A1 ANTI-MUSK ANTIBODIES FOR USE IN TREATING NEUROMUSCULAR DISORDERS MUSK, ACHE, CHRM3 HIF1A 4634/4885SMN1; SMN2 48/4885CYP1A2 4683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.