Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412614 | 0.75 | NFKB1 (0.33) | NFKB1NFKB2RELAMAPK1 | |
| SCHEMBL9932801 | 0.72 | ALDH1A1 (0.36) | CYP2C19CYP2C9HIF1AMAPTKMT2A | |
| SCHEMBL16283604 | 0.71 | MAPT (0.41) | CYP2C19CYP2C9HIF1AMAPTKMT2A | |
| SCHEMBL11625994 | 0.69 | BRD4 (0.41) | CYP2C19CYP2C9LMNAHDAC8 | |
| SCHEMBL9669676 | 0.69 | CYP2C19 (0.39) | CYP2C19CYP2C9HIF1AMAPTKMT2A | |
| SCHEMBL9971685 | 0.67 | PLAU (0.34) | CYP2C19CYP2C9HIF1AMAPTKMT2A | |
| SCHEMBL11467541 | 0.66 | MCL1 (0.44) | CYP2C19CYP2C9MAPTKMT2AMT-CO2 | |
| SCHEMBL11873477 | 0.64 | CYP2C9 (0.38) | CYP2C19CYP2C9MAPK1LMNACYP2B6 | |
| SCHEMBL24342011 | 0.63 | MAPK1 (0.41) | NFKB1NFKB2RELACYP2C19HIF1A | |
| SCHEMBL7052576 | 0.63 | MAPK1 (0.41) | NFKB1NFKB2RELACYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084227-A1 | THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM | Sabic Innovative Plastics IP B.V. (NL) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008063724-A1 | THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-05-29 | — | — | WO | disclosed |
| EP-0694572-B1 | A method for manufacturing polycarbonate | GEN ELECTRIC (US) | 2000-05-10 | — | — | EP | disclosed |
| EP-0694572-A2 | A method for manufacturing polycarbonate | GENERAL ELECTRIC COMPANY (US) | 1996-01-31 | — | — | EP | disclosed |