Sugi Predict

Sugi Predict / Compounds / SCHEMBL9932801

SCHEMBL9932801

SCHEMBL9932801

CC(C)(c1ccccc1)C1CC(=O)OC1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.36
▸ CTRC Q99895 1/20 0.35
▸ CYP2C19 P33261 2/20 0.34
▸ HIF1A Q16665 1/20 0.34
▸ CTRB1 P17538 1/20 0.34
▸ ALDH2 P05091 1/20 0.34
▸ MAPT P10636 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ RECQL P46063 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ KCNN4 O15554 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ MT-CO2 P00403 1/20 0.31
▸ ALOX5 P09917 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9971685 0.83 PLAU (0.34) CYP2C19HIF1AMAPTKMT2ACYP2C9
SCHEMBL11624413 0.81 L3MBTL1 (0.39) ALDH1A1HIF1AMAPTKMT2AMEN1
SCHEMBL21091813 0.74 ALDH1A1 (0.34) ALDH1A1CTRCMAPTKMT2AMEN1
SCHEMBL8853723 0.73 SMN1; SMN2 (0.33) ALDH1A1SMN1; SMN2
SCHEMBL3373990 0.73 SMN1; SMN2 (0.33) ALDH1A1SMN1; SMN2
SCHEMBL4248469 0.72 NFKB1 (0.38) CYP2C19HIF1AMAPTKMT2ACYP2C9
SCHEMBL16283604 0.71 MAPT (0.41) ALDH1A1CYP2C19HIF1AMAPTKMT2A
SCHEMBL28859583 0.70 LMNA (0.35) ALDH1A1CYP2C19CYP2C9GAASMN1; SMN2
SCHEMBL9669676 0.69 CYP2C19 (0.39) ALDH1A1CYP2C19HIF1AMAPTKMT2A
SCHEMBL19601183 0.68 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4158090-A RESIDUE OF DIMETHYLBENZYL SUCCINIC ANHYDRIDE AND 5-PHENYL-5-METHYLHEXANE-1,2,3,4-TETRACARBOXYLIC ACID ANHYDRIDE AND A CURING AGENT GULF RESEARCH & DEVELOPMENT COMPANY (US) 1979-06-12 — — US claimed
US-4147856-A Epoxy resin compositions (Case A) containing cumene-maleic anhydride residue GULF RESEARCH & DEVELOPMENT COMPANY (US) 1979-04-03 — — US claimed
US-9073838-B2 Method of making indeno-fused naphthol materials TRANSITIONS OPTICAL, INC. (US) 2015-07-07 — — US disclosed
US-9073838-B2 Method of making indeno-fused naphthol materials TRANSITIONS OPTICAL, INC. (US) 2015-07-07 — — US disclosed
EP-2651914-B1 PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS TRANSITIONS OPTICAL INC (US) 2015-05-13 — — EP disclosed
US-8920928-B2 Photochromic compounds and compositions TRANSITIONS OPTICAL, INC. (US) 2014-12-30 — — US disclosed
US-20140364618-A1 Method of Making Indeno-Fused Naphthol Materials TRANSITIONS OPTICALS, INC. (US) 2014-12-11 — — US disclosed
US-20140364618-A1 Method of Making Indeno-Fused Naphthol Materials TRANSITIONS OPTICALS, INC. (US) 2014-12-11 — — US disclosed
US-8765978-B2 Method of making indeno-fused naphthol materials TRANSITIONS OPTICAL, INC. (US) 2014-07-01 — — US disclosed
US-8765978-B2 Method of making indeno-fused naphthol materials TRANSITIONS OPTICAL, INC. (US) 2014-07-01 — — US disclosed
EP-2651914-A1 PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS Transitions Optical, Inc. (US) 2013-10-23 — — EP disclosed
US-4158090-A RESIDUE OF DIMETHYLBENZYL SUCCINIC ANHYDRIDE AND 5-PHENYL-5-METHYLHEXANE-1,2,3,4-TETRACARBOXYLIC ACID ANHYDRIDE AND A CURING AGENT GULF RESEARCH & DEVELOPMENT COMPANY (US) 1979-06-12 — — US disclosed
US-4147856-A Epoxy resin compositions (Case A) containing cumene-maleic anhydride residue GULF RESEARCH & DEVELOPMENT COMPANY (US) 1979-04-03 — — US disclosed
US-4147856-A Epoxy resin compositions (Case A) containing cumene-maleic anhydride residue GULF RESEARCH & DEVELOPMENT COMPANY (US) 1979-04-03 — — US disclosed
US-4132697-A LIQUID IMPREGNANT AS A FIBER REINFORCING BINDER GULF RESEARCH & DEVELOPMENT COMPANY (US) 1979-01-02 — — US disclosed
US-4122050-A POLYCYCLIC AROMATIC POLYCARBOXYLIC ACIDS FROM NITRIC ACID OXIDATION OF COAL, FOAMING AGENTS GULF RESEARCH & DEVELOPMENT COMPANY (US) 1978-10-24 — — US disclosed
US-4122185-A 2-Phenyl- and 2-benzyl-N-[(trichloromethyl)thio]succinimides, and fungicidal compositions thereof STERLING DRUG INC. (US) 1978-10-24 — — US disclosed
US-4101469-A NITROAROMATIC POLYCARBOXYLIC ACIDS GULF RESEARCH & DEVELOPMENT COMPANY (US) 1978-07-18 — — US disclosed
US-4041004-A Polyepoxy-3,3',4,4'-benzhydrol tetracarboxylic dianhydride laminating resins GULF RESEARCH & DEVELOPMENT COMPANY (US) 1977-08-09 — — US disclosed
US-3996185-A Polyepoxy resin-diaryl dianhydride laminating resins and laminates GULF RESEARCH & DEVELOPMENT COMPANY (US) 1976-12-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140364618-A1 Method of Making Indeno-Fused Naphthol Materials IDH3A, NQO1, IDH3B ALDH1A1 494/4885CTRC 3204/4885CYP2C19 209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.