Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 6/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 6/20 | 0.39 |
| ▸ | RELA | Q04206 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24342011 | 1.00 | MAPK1 (0.41) | MAPK1NFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL8578253 | 0.83 | NFKB1 (0.41) | NFKB1NFKB2RELA | |
| SCHEMBL8577970 | 0.77 | NFKB1 (0.46) | MAPK1NFKB1NFKB2RELA | |
| SCHEMBL7051372 | 0.69 | ALDH1A1 (0.44) | MAPK1ALDH1A1ALOX15CYP2C19HIF1A | |
| SCHEMBL7051771 | 0.69 | ALDH1A1 (0.44) | MAPK1ALDH1A1ALOX15CYP2C19HIF1A | |
| SCHEMBL7050025 | 0.69 | ALDH1A1 (0.44) | MAPK1ALDH1A1ALOX15CYP2C19HIF1A | |
| SCHEMBL7051369 | 0.69 | ALDH1A1 (0.44) | MAPK1ALDH1A1ALOX15CYP2C19HIF1A | |
| SCHEMBL7051770 | 0.69 | ALDH1A1 (0.44) | MAPK1ALDH1A1ALOX15CYP2C19HIF1A | |
| SCHEMBL7047885 | 0.68 | ALDH1A1 (0.40) | MAPK1ALDH1A1ALOX15MAPTKMT2A | |
| SCHEMBL7047888 | 0.68 | ALDH1A1 (0.40) | MAPK1ALDH1A1ALOX15MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086942-B1 | Optically active alcohols and processes for the preparation thereof | CHISSO CORP (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-1086942-A1 | Optically active alcohols and processes for the preparation thereof | CHISSO CORPORATION (JP) | 2001-03-28 | — | — | EP | disclosed |
| EP-0299907-B1 | Process for the preparation of diesters of symmetrical bicyclo[3.3.0]octanedionedicarboxylic acids | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-03-04 | — | — | EP | disclosed |
| US-4912251-A | Process for manufacturing symmetrical diesters of bicyclo[3.3.0]-octanedione dicarboxylic acid | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | disclosed |
| WO-1989000555-A1 | PROCESS FOR MANUFACTURING SYMMETRICAL DIESTERS OF BICYCLO[3.3.0]-OCTANEDIONE DICARBOXYLIC ACID | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299907-A1 | Process for the preparation of diesters of symmetrical bicyclo[3.3.0]octanedionedicarboxylic acids | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-01-18 | — | — | EP | disclosed |