Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 11/20 | 0.47 |
| ▸ | MMP13 | P45452 | 11/20 | 0.47 |
| ▸ | MMP1 | P03956 | 11/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378971 | 0.76 | MMP13 (0.49) | MMP9MMP13MMP1HTTMMP2 | |
| SCHEMBL8559637 | 0.75 | MMP13 (0.72) | MMP9MMP13MMP1MMP2MMP3 | |
| SCHEMBL7372083 | 0.74 | CA12 (0.54) | MMP13MMP1LMNATSHRSMN1; SMN2 | |
| SCHEMBL7516170 | 0.74 | GAA (0.49) | MMP9MMP13MMP1HTTCA12 | |
| SCHEMBL2761358 | 0.73 | HTT (0.55) | MMP9MMP13MMP1HTTMMP2 | |
| SCHEMBL6932195 | 0.71 | MMP13 (0.63) | MMP9MMP13MMP1MMP2MMP3 | |
| Ethylamine SCHEMBL7956386 | 0.71 | MMP13 (0.57) | MMP9MMP13MMP1CA12CA1 | |
| SCHEMBL2518753 | 0.71 | CA12 (0.41) | MMP9MMP13MMP1PPARATSHR | |
| SCHEMBL28026557 | 0.71 | SMN1; SMN2 (0.49) | MMP9MMP13MMP1LMNASMN1; SMN2 | |
| SCHEMBL28026558 | 0.71 | SMN1; SMN2 (0.49) | MMP9MMP13MMP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085379-A1 | Arylsulfonamido-substituted hydroxamic acid derivatives | Novartis AG (CH) | 2009-08-05 | — | — | EP | disclosed |