Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 10/20 | 0.48 |
| ▸ | MMP13 | P45452 | 10/20 | 0.48 |
| ▸ | MMP1 | P03956 | 9/20 | 0.48 |
| ▸ | PTPRB | P23467 | 1/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559637 | 0.77 | MMP13 (0.72) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7511963 | 0.74 | MMP9 (0.58) | MMP9MMP13MMP1CA12CA1 | |
| SCHEMBL4249034 | 0.74 | MMP9 (0.47) | MMP9MMP13MMP1CA12CA1 | |
| SCHEMBL7378971 | 0.72 | MMP13 (0.49) | GAAPKMMMP9MMP13MMP1 | |
| SCHEMBL503526 | 0.70 | BLM (0.67) | GAAPTPRBCA12CA1CA2 | |
| SCHEMBL540243 | 0.70 | BLM (0.67) | GAAPTPRBCA12CA1CA2 | |
| SCHEMBL503525 | 0.70 | BLM (0.67) | GAAPTPRBCA12CA1CA2 | |
| SCHEMBL3266754 | 0.70 | PTPRB (0.71) | GAAPTPRBHTT | |
| SCHEMBL7389414 | 0.70 | MMP3 (0.54) | MMP9MMP13MMP1ALDH1A1 | |
| SCHEMBL3935038 | 0.70 | TSHR (0.46) | GAAPKMMMP9MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202961-A1 | ARYLSULFONAMIDO-SUBSTITUTED HYDROXAMIC ACID DERIVATIVES | Novartis AG (CH) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001010827-A1 | ARYLSULFONAMIDO-SUBSTITUTED HYDROXAMIC ACID DERIVATIVES | NOVARTIS AG (CH) | 2001-02-15 | — | — | WO | disclosed |