Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4256865 | 0.87 | CCR3 (0.55) | CCR3HTR1ASLC6A4 | |
| SCHEMBL4255676 | 0.87 | CCR3 (0.60) | CCR3HDAC1HDAC8HDAC6 | |
| SCHEMBL7403790 | 0.78 | CCR3 (1.00) | CCR3SIGMAR1HTR1ASLC6A4HRH3 | |
| Hydrochloric Acid SCHEMBL7404097 | 0.76 | CCR3 (0.97) | CCR3SIGMAR1HTR1ASLC6A4HRH3 | |
| SCHEMBL7407241 | 0.76 | CCR3 (0.82) | CCR3SIGMAR1 | |
| SCHEMBL4255240 | 0.75 | HRH3 (0.51) | HRH3 | |
| SCHEMBL23123778 | 0.75 | CCR3 (0.61) | CCR3HTR2ASIGMAR1HDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL7410288 | 0.75 | CCR3 (0.80) | CCR3SIGMAR1 | |
| SCHEMBL4259804 | 0.75 | ALDH1A1 (0.61) | CCR3 | |
| SCHEMBL1918964 | 0.73 | CCR3 (0.73) | CCR3HTR2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239860-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-1710233-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2006-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239860-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | ADORA2A, ADORA2B, HTR1F | CCR3 2934/4885HTR2A 6/4885SIGMAR1 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.