Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 4/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4259804 | 0.89 | ALDH1A1 (0.61) | CCR3ALDH1A1NPSR1 | |
| SCHEMBL4249601 | 0.87 | CCR3 (0.62) | CCR3HTR1ASLC6A4 | |
| SCHEMBL4257514 | 0.78 | ALDH1A1 (0.54) | ALDH1A1NPSR1 | |
| SCHEMBL4255676 | 0.75 | CCR3 (0.60) | CCR3ALDH1A1 | |
| SCHEMBL29826183 | 0.74 | KDM4E (0.52) | ALDH1A1NPSR1 | |
| SCHEMBL6631280 | 0.74 | LTA4H (0.69) | CCR3HTR1ASLC6A4LTA4H | |
| SCHEMBL6206626 | 0.74 | LTA4H (0.69) | CCR3HTR1ASLC6A4LTA4H | |
| SCHEMBL7403790 | 0.73 | CCR3 (1.00) | CCR3HTR1ASLC6A4 | |
| SCHEMBL18191776 | 0.73 | HTR2A (0.66) | ALDH1A1NPSR1OPRM1LTA4H | |
| SCHEMBL23123778 | 0.73 | CCR3 (0.61) | CCR3LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239860-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-1710233-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2006-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239860-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | ADORA2A, ADORA2B, HTR1F | CCR3 2934/4885HTR1A 7/4885SLC6A4 406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.