Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | AGXT | P21549 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416033 | 0.83 | CASR (0.57) | CASRALDH1A1CHRM2HTTSMN1; SMN2 | |
| SCHEMBL2954251 | 0.79 | CASR (0.60) | CASRALDH1A1CHRM2HTTSMN1; SMN2 | |
| SCHEMBL4249926 | 0.78 | CASR (0.52) | CASRALDH1A1CHRM2HTTSMN1; SMN2 | |
| SCHEMBL3348575 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HTTSMN1; SMN2MMP13MEN1 | |
| SCHEMBL7738530 | 0.77 | CHRM2 (0.62) | ALDH1A1CHRM2HTTSMN1; SMN2MMP13 | |
| SCHEMBL18685365 | 0.77 | CHRM2 (0.62) | ALDH1A1CHRM2HTTSMN1; SMN2MMP13 | |
| SCHEMBL27646012 | 0.76 | DNM1 (0.58) | ALDH1A1CHRM2HTTSMN1; SMN2MMP13 | |
| SCHEMBL2076794 | 0.75 | CHRM2 (0.60) | ALDH1A1CHRM2HTTSMN1; SMN2MMP13 | |
| Hydrochloric Acid SCHEMBL28327424 | 0.75 | CHRM2 (0.60) | ALDH1A1CHRM2HTTSMN1; SMN2MMP13 | |
| SCHEMBL23385049 | 0.75 | CASR (0.52) | CASRALDH1A1CHRM2HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213407-A1 | Compounds to treat Alzheimer's disease | ELAN PHARMACEUTICALS AND PHARMACIA & UPJOHN COMPANY LLC | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213407-A1 | Compounds to treat Alzheimer's disease | PSEN2, PSEN1, CHAT | CASR 2993/4885ALDH1A1 524/4885CHRM2 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.