Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10350961 | 0.77 | HTT (0.56) | KDM4EALDH1A1PKMPIK3CA | |
| SCHEMBL11419973 | 0.77 | SELL (0.56) | KDM4EALDH1A1PKMPIK3CA | |
| SCHEMBL4511328 | 0.76 | DRD2 (0.67) | HRH1CHRM1DRD2DRD4CHRM2 | |
| SCHEMBL3650265 | 0.76 | HTT (0.63) | KDM4EALDH1A1PKMPIK3CA | |
| SCHEMBL7773826 | 0.75 | SELL (0.54) | KDM4EALDH1A1PKMPIK3CA | |
| SCHEMBL10794438 | 0.74 | HTT (0.61) | KDM4EALDH1A1PIK3CA | |
| SCHEMBL10351740 | 0.74 | HTT (0.61) | KDM4EALDH1A1PIK3CA | |
| SCHEMBL10350952 | 0.74 | HTT (0.61) | KDM4EALDH1A1PIK3CA | |
| SCHEMBL9806444 | 0.74 | HTT (0.61) | KDM4EALDH1A1PIK3CA | |
| SCHEMBL8823487 | 0.74 | HTT (0.61) | KDM4EALDH1A1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176802-A1 | ANTIDOTES TO EXOGENOUS NEUROTOXIC AGENTS | PAPADOPOULOS VASSILIOS | 2009-07-09 | — | — | US | claimed |
| WO-2007092458-A1 | ANTIDOTES TO EXOGENOUS NEUROTOXIC AGENTS | SAMARITAN PHARMACEUTICALS, INC. (US) | 2007-08-16 | — | — | WO | claimed |
| US-20060247248-A1 | Sigma-1 receptor ligand with acetylcholinesterase | SAMARITAN PHARMACEUTICALS, INC. | 2006-11-02 | — | — | US | claimed |
| US-20090176802-A1 | ANTIDOTES TO EXOGENOUS NEUROTOXIC AGENTS | PAPADOPOULOS VASSILIOS | 2009-07-09 | — | — | US | disclosed |
| US-20060247248-A1 | Sigma-1 receptor ligand with acetylcholinesterase | SAMARITAN PHARMACEUTICALS, INC. | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247248-A1 | Sigma-1 receptor ligand with acetylcholinesterase | SIGMAR1, CHRNE, ACHE | TSHR 786/4885HRH1 307/4885CHRM1 13/4885 |
| US-20090176802-A1 | ANTIDOTES TO EXOGENOUS NEUROTOXIC AGENTS | INA, ACHE, NLN | TSHR 1662/4885HRH1 2753/4885CHRM1 603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.