Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194392 | 0.86 | KEAP1 (0.57) | PLCG1KEAP1NFE2L2RAPGEF4ALDH1A1 | |
| SCHEMBL3882288 | 0.86 | PSIP1 (0.50) | PLCG1KEAP1NFE2L2RAPGEF4ALDH1A1 | |
| SCHEMBL27519579 | 0.82 | KEAP1 (0.46) | PLCG1KEAP1NFE2L2RAPGEF4ALDH1A1 | |
| SCHEMBL8765877 | 0.82 | KEAP1 (0.46) | PLCG1KEAP1NFE2L2RAPGEF4ALDH1A1 | |
| SCHEMBL11692985 | 0.82 | KEAP1 (0.46) | KEAP1NFE2L2RAPGEF4ALDH1A1ALOX12 | |
| SCHEMBL27498526 | 0.82 | KEAP1 (0.46) | PLCG1KEAP1NFE2L2RAPGEF4ALDH1A1 | |
| SCHEMBL385916 | 0.82 | KEAP1 (0.46) | PLCG1KEAP1NFE2L2RAPGEF4ALDH1A1 | |
| SCHEMBL9703985 | 0.82 | KEAP1 (0.46) | PLCG1KEAP1NFE2L2RAPGEF4ALDH1A1 | |
| SCHEMBL6097634 | 0.80 | KEAP1 (0.53) | KEAP1NFE2L2RAPGEF4ALDH1A1ALOX12 | |
| SCHEMBL14495116 | 0.79 | KEAP1 (0.51) | PLCG1KEAP1NFE2L2RAPGEF4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2623539-B1 | PROCESS FOR PRODUCTION OF POLY(LACTIC ACID)-TYPE RESIN, AND POLY(LACTIC ACID)-TYPE PREPOLYMER | NATUREWORKS LLC (US) | 2017-11-08 | — | — | EP | disclosed |
| US-9023953-B2 | Process for production of poly(lactic acid)-type resin, and poly(lactic acid)-type prepolymer | TORAY INDUSTRIES, INC. (JP) | 2015-05-05 | — | — | US | disclosed |
| EP-2623539-A1 | PROCESS FOR PRODUCTION OF POLY(LACTIC ACID)-TYPE RESIN, AND POLY(LACTIC ACID)-TYPE PREPOLYMER | Toray Industries, Inc. (JP) | 2013-08-07 | — | — | EP | disclosed |
| US-20130197186-A1 | PROCESS FOR PRODUCTION OF POLY(LACTIC ACID)-TYPE RESIN, AND POLY(LACTIC ACID)-TYPE PREPOLYMER | TORAY INDUSTRIES INC (JP) | 2013-08-01 | — | — | US | disclosed |
| US-7638654-B2 | 1-fluoro-1, 1-bis-(phenylsulfonyl)methane and production method thereof | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20090131723-A1 | 1-Fluoro-1,1-Bis-(Phenylsulfonyl)Methane and Production Method Thereof | TOSOH F-TECH, INC. (JP) | 2009-05-21 | — | — | US | disclosed |
| EP-1992612-A1 | 1-FLUORO-1,1-BIS(PHENYLSULFONYL)METHANE AND METHOD FOR PRODUCING SAME | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2008-11-19 | — | — | EP | disclosed |
| US-6183934-B1 | FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE | KABUSHIKI KAISHA TOSHIBA (JP) | 2001-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131723-A1 | 1-Fluoro-1,1-Bis-(Phenylsulfonyl)Methane and Production Method Thereof | CYP2S1, ARSA, MSMO1 | PLCG1 1435/4885KEAP1 667/4885NFE2L2 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.