Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14495116 | 0.83 | KEAP1 (0.51) | KEAP1NFE2L2RAPGEF4ALDH1A1HTT | |
| SCHEMBL3882288 | 0.82 | PSIP1 (0.50) | KEAP1NFE2L2RAPGEF4ALDH1A1HTT | |
| SCHEMBL7194392 | 0.82 | KEAP1 (0.57) | KEAP1NFE2L2RAPGEF4ALDH1A1HTT | |
| SCHEMBL4250262 | 0.82 | PLCG1 (0.56) | KEAP1NFE2L2RAPGEF4ALDH1A1HTT | |
| SCHEMBL2734646 | 0.79 | KEAP1 (0.59) | KEAP1NFE2L2RAPGEF4ALDH1A1HTT | |
| SCHEMBL9703985 | 0.78 | KEAP1 (0.46) | KEAP1NFE2L2RAPGEF4ALDH1A1HTT | |
| SCHEMBL27519579 | 0.78 | KEAP1 (0.46) | KEAP1NFE2L2RAPGEF4ALDH1A1HTT | |
| SCHEMBL27498526 | 0.78 | KEAP1 (0.46) | KEAP1NFE2L2RAPGEF4ALDH1A1HTT | |
| SCHEMBL385916 | 0.78 | KEAP1 (0.46) | KEAP1NFE2L2RAPGEF4ALDH1A1HTT | |
| SCHEMBL11692985 | 0.78 | KEAP1 (0.46) | KEAP1NFE2L2RAPGEF4ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619303-B1 | 4-alkyl-3-chloro-benzenesulfinic acids, 4-alkyl-3-chloro-benzenesulfonic acids, 4-alkyl-3-chloro-alkylsulfonylbenzenes and process for their preparation | HOECHST AG (DE) | 1997-08-13 | — | — | EP | disclosed |
| US-5498798-A | 4-alkyl-3-chlorobenzenesulfinic acids, 4-alkyl-3-chlorobenzenesulfonylcarboxylic acids, 4-alkyl-3-chloroalkylsulfonylbenzenes and preparation thereof | HOECHST AG (DE) | 1996-03-12 | — | — | US | disclosed |
| EP-0619303-A1 | 4-alkyl-3-chloro-benzenesulfinic acids, 4-alkyl-3-chloro-benzenesulfonic acids, 4-alkyl-3-chloro-alkylsulfonylbenzenes and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-12 | — | — | EP | disclosed |