⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191256 | 0.83 | ALDH1A1 (0.63) | — | |
| SCHEMBL96641 | 0.82 | — | — | |
| SCHEMBL1049265 | 0.80 | ALDH1A1 (0.61) | — | |
| SCHEMBL14521387 | 0.79 | — | — | |
| SCHEMBL2779760 | 0.79 | — | — | |
| SCHEMBL9432303 | 0.78 | ALDH1A1 (0.58) | — | |
| SCHEMBL5948495 | 0.78 | ALDH1A1 (0.74) | — | |
| SCHEMBL131476 | 0.78 | ALDH1A1 (0.74) | — | |
| SCHEMBL9307314 | 0.75 | — | — | |
| SCHEMBL425264 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024141444-A1 | NEW BENZIMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-07-04 | — | — | WO | claimed |
| CN-113710664-B | JAK1 selective kinase inhibitors | 迪哲(江苏)医药股份有限公司 | 2024-01-26 | — | — | CN | claimed |
| US-20220220096-A1 | JAK1 SELECTIVE KINASE INHIBITOR | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2022-07-14 | — | — | US | claimed |
| EP-3956322-A1 | JAK1 SELECTIVE KINASE INHIBITOR | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2022-02-23 | — | — | EP | claimed |
| CN-113710664-A | JAK1 selective kinase inhibitors | 迪哲(江苏)医药股份有限公司 | 2021-11-26 | — | — | CN | claimed |
| WO-2020211839-A1 | JAK1 SELECTIVE KINASE INHIBITOR | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2020-10-22 | — | — | WO | claimed |
| US-7521396-B2 | Substituted (thioxo)carbonylaminophenyluracils | BAYER CROPSCIENCE AG (DE) | 2009-04-21 | — | — | US | claimed |
| US-20060089262-A1 | Substituted (thioxo)carbonylamino phenyl uraciles | BAYER CROPSCIENCE AG (DE) | 2006-04-27 | — | — | US | claimed |
| US-6992044-B1 | Substituted phenyluracils | BAYER CROPSCIENCE AG (DE) | 2006-01-31 | — | — | US | claimed |
| EP-1503994-A1 | SUBSTITUTED (THIOXO)CARBONYLAMINO PHENYL URACILES | Bayer CropScience AG (DE) | 2005-02-09 | — | — | EP | claimed |
| WO-2003093244-A1 | SUBSTITUTED (THIOXO)CARBONYLAMINO PHENYL URACILES | BAYER CROPSCIENCE AG (DE) | 2003-11-13 | — | — | WO | claimed |
| EP-1330443-A1 | SUBSTITUTED PHENYLURACILS | Bayer CropScience AG (DE) | 2003-07-30 | — | — | EP | claimed |
| CN-1420873-A | Substituted phenyluracils | BAYER AG (DE) | 2003-05-28 | — | — | CN | claimed |
| EP-1272478-A1 | SUBSTITUTED PHENYLURACILS | Bayer Aktiengesellschaft (DE) | 2003-01-08 | — | — | EP | claimed |
| US-20020173425-A1 | Substituted phenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-21 | — | — | US | claimed |
| WO-2002034725-A1 | SUBSTITUTED PHENYLURACILS | BAYER CROPSCIENCE AG (DE) | 2002-05-02 | — | — | WO | claimed |
| WO-2001077084-A1 | SUBSTITUTED PHENYLURACILS | BAYER CROPSCIENCE AG (DE) | 2001-10-18 | — | — | WO | claimed |
| EP-0832082-A1 | N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1998-04-01 | — | — | EP | claimed |
| WO-1996040681-A1 | N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1996-12-19 | — | — | WO | claimed |
| US-3957815-A | 3-[3',4'-Dichloro-6'-alkyl-phenyl]-Δ2 -pyrazoline derivatives and their use as optical brighteners | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | claimed |