⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1049265 | 0.92 | ALDH1A1 (0.61) | — | |
| SCHEMBL9432303 | 0.90 | ALDH1A1 (0.58) | — | |
| SCHEMBL5948495 | 0.85 | ALDH1A1 (0.74) | — | |
| SCHEMBL131476 | 0.85 | ALDH1A1 (0.74) | — | |
| SCHEMBL425263 | 0.82 | — | — | |
| SCHEMBL3189950 | 0.82 | ALDH1A1 (0.70) | — | |
| SCHEMBL1191256 | 0.78 | ALDH1A1 (0.63) | — | |
| SCHEMBL96642 | 0.78 | — | — | |
| SCHEMBL9210592 | 0.78 | — | — | |
| SCHEMBL827843 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464623-B1 | THE RING OPENING OF LACTONES AND LACTAMS | NOVARTIS AG (CH) | 2020-11-04 | — | — | EP | disclosed |
| US-20200308109-A1 | FLUORENE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2020-10-01 | — | — | US | disclosed |
| US-20190177271-A1 | FLUORENE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2019-06-13 | — | — | US | disclosed |
| US-20150329491-A1 | FLUORENE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2015-11-19 | — | — | US | disclosed |
| US-20150266839-A1 | CYCLIC AMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-09-24 | — | — | US | disclosed |
| US-20150225392-A1 | CYCLIC AMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-08-13 | — | — | US | disclosed |
| US-9072758-B2 | Cyclic amide derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-07-07 | — | — | US | disclosed |
| EP-2345629-B1 | FLUORENE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | JAPAN TOBACCO INC (JP) | 2015-06-03 | — | — | EP | disclosed |
| US-9040525-B2 | Cyclic amide derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-05-26 | — | — | US | disclosed |
| US-8871934-B2 | Fluorene compound and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2014-10-28 | — | — | US | disclosed |
| US-5387596-A | Treating arteriosclerosis | SANKYO COMPANY, LIMITED (JP) | 1995-02-07 | — | — | US | disclosed |
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0566226-A1 | Quinazoline derivatives | ZENECA LIMITED (GB) | 1993-10-20 | — | — | EP | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |
| US-4962014-A | USING SULFITE CONTAINING BLIXING LIQUID TO SHORTEN TIME AND REDUCE WATER CONSUMPTION WITHOUT IMPAIRING STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1990-10-09 | — | — | US | disclosed |
| US-4914007-A | REDUCING THE WATER WASHING TIME OF CONTINUOUS COLOR DEVELOPMENT | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| US-4588677-A | 4-MERCAPTO-5-PYRAZOLONE TYPE MAGENTA COUPLERS | FUJI PHOTO FILM CO., LTD. (JP) | 1986-05-13 | — | — | US | disclosed |
| US-4584266-A | 2-EQUIVALENT 5-PYRAZOLONE MAGENTA COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1986-04-22 | — | — | US | disclosed |
| US-4107329-A | Fluorinated compounds as therapeutics | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-08-15 | — | — | US | disclosed |
| US-4067996-A | HYPOLIPEMIC, HYPOCHOLESTEROLEMIC | SYNTHELABO (FR) | 1978-01-10 | — | — | US | disclosed |