Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | LDHA | P00338 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.55 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4253000 | 0.85 | CASP3 (0.61) | RAB9AALDH1A1SMN1; SMN2NPC1DYRK1A | |
| SCHEMBL4253988 | 0.85 | MAOA (0.65) | RAB9AALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL4252873 | 0.77 | CNR1 (0.63) | RAB9AALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL30561486 | 0.74 | DYRK1A (0.79) | RAB9AALDH1A1HPGDLDHASMN1; SMN2 | |
| SCHEMBL19807983 | 0.74 | DYRK1A (0.79) | RAB9AALDH1A1HPGDLDHASMN1; SMN2 | |
| SCHEMBL10596177 | 0.74 | RAB9A (0.81) | RAB9AALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL17856947 | 0.74 | KMT2A (0.92) | RAB9AALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL4923582 | 0.74 | RAB9A (0.69) | RAB9AALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL1651188 | 0.74 | PIK3CG (0.80) | RAB9ALDHASMN1; SMN2NPC1DYRK1A | |
| SCHEMBL10170616 | 0.73 | DYRK1A (1.00) | RAB9ASMN1; SMN2NPC1DYRK1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170914-A1 | Cermide Kinase Modulation | BORNANCIN FREDERIC | 2009-07-02 | — | — | US | claimed |
| US-20090170914-A1 | Cermide Kinase Modulation | BORNANCIN FREDERIC | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170914-A1 | Cermide Kinase Modulation | CERS2, CHKB, SPHK2 | RAB9A 566/4885ALDH1A1 4781/4885KDM4E 1374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.